Target Name: POF1B
NCBI ID: G79983
Review Report on POF1B Target / Biomarker Content of Review Report on POF1B Target / Biomarker
POF1B
Other Name(s): POF1B_HUMAN | premature ovarian failure, 1B | premature ovarian failure protein 1B | Protein POF1B (isoform 1) | POF1B variant 1 | POF2B | POF | Premature ovarian failure protein 1B | POF1B actin binding protein, transcript variant 1 | POF1B actin binding protein | Protein POF1B

POF1B: A Potential Drug Target and Biomarker

Proteasome-associated protein 1B (POF1B) is a protein that is expressed in various tissues throughout the body. It plays a crucial role in the regulation of protein degradation and has been implicated in a number of cellular processes. Despite its importance, little is known about POF1B. In this article, we will explore the potential implications of POF1B as a drug target and highlight its potential as a biomarker.

POF1B as a Drug Target

The identification of potential drug targets is an important aspect of drug development. POF1B has been shown to play a role in a number of cellular processes, including cell survival, proliferation, and stress resistance. Its involvement in these processes makes it an attractive target for drug development.

One potential mechanism by which POF1B could be targeted is through its role in the regulation of protein degradation. POF1B has been shown to interact with the protein degradation machinery, known as the 26S proteasome. This interaction suggests that POF1B may play a role in the regulation of protein degradation, which could be potential target for drugs that target protein synthesis or degradation.

Another potential mechanism by which POF1B could be targeted is through its role in cell stress resistance. POF1B has been shown to play a role in the regulation of cellular stress responses, including the response to oxidative stress. Its involvement in these processes makes it an attractive target for drugs that are designed to improve cellular stress resilience.

POF1B as a Biomarker

The identification of biomarkers is an important aspect of drug development. POF1B has been shown to play a role in a number of cellular processes, including cell survival, proliferation, and stress resistance. Its involvement in these processes makes it an attractive biomarker for a variety of diseases.

One potential use for POF1B as a biomarker is its potential to serve as a marker for cancer. POF1B has been shown to be expressed in a variety of cancer types, including breast, lung, and colorectal cancers. Its expression has also been associated with the development of cancer in animal models. Therefore, POF1B could be used as a biomarker for cancer diagnosis and monitoring.

Another potential use for POF1B as a biomarker is its potential to serve as a marker for neurodegenerative diseases. POF1B has been shown to play a role in the regulation of protein synthesis and degradation in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Therefore, POF1B could be used as a biomarker for the diagnosis and monitoring of these conditions.

Conclusion

In conclusion, POF1B is a protein that has been shown to play a role in various cellular processes. Its involvement in these processes makes it an attractive target for drug development. As a drug target, POF1B has the potential to be used to treat a variety of diseases, including cancer and neurodegenerative diseases. As a biomarker, POF1B has the potential to be used to diagnose and monitor a variety of diseases. Further research is needed to fully understand the role of POF1B in these processes and its potential as a drug and biomarker.

Protein Name: POF1B Actin Binding Protein

Functions: Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development

The "POF1B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about POF1B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

POFUT1 | POFUT2 | POGK | POGLUT1 | POGLUT2 | POGLUT3 | POGZ | POLA1 | POLA2 | POLB | POLD1 | POLD2 | POLD3 | POLD4 | POLDIP2 | POLDIP3 | POLE | POLE2 | POLE3 | POLE4 | POLG | POLG2 | POLH | POLI | POLK | POLL | POLM | POLN | POLQ | POLR1A | POLR1B | POLR1C | POLR1D | POLR1E | POLR1F | POLR1G | POLR1H | POLR1HASP | POLR2A | POLR2B | POLR2C | POLR2D | POLR2E | POLR2F | POLR2G | POLR2H | POLR2I | POLR2J | POLR2J2 | POLR2J3 | POLR2J4 | POLR2K | POLR2L | POLR2LP1 | POLR2M | POLR3A | POLR3B | POLR3C | POLR3D | POLR3E | POLR3F | POLR3G | POLR3GL | POLR3H | POLR3K | POLRMT | POLRMTP1 | Poly [ADP-ribose] polymerase | Polycomb Repressive Complex 1 (PRC1) | Polycomb Repressive Complex 2 | POM121 | POM121B | POM121C | POM121L12 | POM121L15P | POM121L1P | POM121L2 | POM121L4P | POM121L7P | POM121L8P | POM121L9P | POMC | POMGNT1 | POMGNT2 | POMK | POMP | POMT1 | POMT2 | POMZP3 | PON1 | PON2 | PON3 | POP1 | POP4 | POP5 | POP7 | POPDC2 | POPDC3 | POR | PORCN