Target Name: PMVK
NCBI ID: G10654
Review Report on PMVK Target / Biomarker Content of Review Report on PMVK Target / Biomarker
PMVK
Other Name(s): hPMK | HUMPMKI | phosphomevalonate kinase | PMVK_HUMAN | PMKA | testis tissue sperm-binding protein Li 95mP | Phosphomevalonate kinase, transcript variant 1 | PMKase | PMK | PMKASE | POROK1 | Phosphomevalonate kinase | PMVK variant 1 | Phosphomevalonate kinase (isoform 1)

PMVK: A protein involved in aging and disease

Progerocytosis modifier (PMVK) is a protein that is expressed in the brain and is known to be a key regulator of the aging process. PMVK is a protein that is highly conserved across species and is found in many different tissues, including brain, heart, and skeletal muscles. PMVK has been shown to play a role in the development and progression of a variety of age-related diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease.

PMVK is a key regulator of the aging process

PMVK is a key regulator of the aging process and has been shown to play a role in the development and progression of many age-related diseases. One of the ways that PMVK contributes to aging is by breaking down cellular components that are important for maintaining cellular health and function. This can lead to the accumulation of damage and dysfunction in the body over time, which can contribute to the development of age-related diseases.

PMVK is involved in the regulation of cellular stress

PMVK is involved in the regulation of cellular stress, which is a critical aspect of maintaining cellular health and function. Stress can cause damage to cellular components and disrupt normal cellular processes, leading to the accumulation of stress-related damage in the body over time. PMVK helps to regulate this process and maintain cellular homeostasis, which is essential for the proper functioning of cells.

PMVK is involved in the regulation of neurodegeneration

PMVK is involved in the regulation of neurodegeneration, which is the progressive loss of brain cells that is associated with a variety of neurological disorders, including Alzheimer's disease and Parkinson's disease. PMVK has been shown to play a role in the development and progression of neurodegeneration by breaking down cellular components that are important for maintaining brain cell health and function. This can lead to the accumulation of damage and dysfunction in the brain over time, which can contribute to the development of neurodegeneration.

PMVK is a potential drug target

PMVK is a potential drug target for the treatment of a variety of age-related diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease. Because PMVK is involved in the regulation of many important cellular processes that are involved in the development and progression of age-related diseases, it is possible that targeting PMVK may be a effective way to treat these conditions.

PMVK is a potential biomarker

PMVK is a potential biomarker for the diagnosis and treatment of age-related diseases. Because PMVK is involved in the regulation of many important cellular processes that are involved in the development and progression of age-related diseases, it is possible that analyzing the levels of PMVK in the body may be a useful diagnostic tool for the diagnosis of these conditions. Additionally, because PMVK is a protein that is highly conserved across species, it is possible that analyzing the levels of PMVK in different tissues or cells may be a useful diagnostic tool for the diagnosis of these conditions.

Conclusion

PMVK is a protein that is highly conserved across species and is involved in the regulation of many important cellular processes that are involved in the development and progression of age-related diseases. PMVK is a potential drug target for the treatment of a variety of age-related conditions and is also a potential biomarker for the diagnosis and treatment of these conditions. Further research is needed to fully understand the role of PMVK in the regulation of aging and the treatment of age-related diseases.

Protein Name: Phosphomevalonate Kinase

Functions: Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites

The "PMVK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PMVK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2 | POC1A | POC1B | POC1B-GALNT4 | POC5 | PODN | PODNL1 | PODXL | PODXL2 | POF1B | POFUT1 | POFUT2 | POGK | POGLUT1 | POGLUT2 | POGLUT3 | POGZ | POLA1 | POLA2 | POLB | POLD1 | POLD2 | POLD3 | POLD4 | POLDIP2 | POLDIP3 | POLE | POLE2 | POLE3 | POLE4 | POLG | POLG2 | POLH | POLI | POLK | POLL | POLM | POLN | POLQ | POLR1A | POLR1B | POLR1C | POLR1D | POLR1E | POLR1F | POLR1G | POLR1H | POLR1HASP | POLR2A | POLR2B | POLR2C | POLR2D | POLR2E | POLR2F | POLR2G | POLR2H | POLR2I | POLR2J | POLR2J2 | POLR2J3 | POLR2J4 | POLR2K | POLR2L | POLR2LP1 | POLR2M | POLR3A