PMPCB: A Protein Involved in Pain, Inflammation and Stress (G9512)

Target Name: PMPCB

NCBI ID: G9512

PMPCB

PMPCB: A Protein Involved in Pain, Inflammation and Stress

PMPCB, or beta-MPP (beta-microglutamyl-proline), is a protein that is expressed in various tissues throughout the body, including the brain, nervous system, and gastrointestinal tract. It is a key regulator of cellular processes that are involved in pain, inflammation, and stress.

Recent studies have identified PMPCB as a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is due to its involvement in the regulation of pain signaling pathways, as well as its role in the regulation of inflammation and cellular stress.

One of the key functions of PMPCB is its role in the regulation of pain signaling pathways. PMPCB is known to play a key role in the regulation of pain transmission from the brain to the body. It has been shown to reduce the pain sensitivity of animals and humans, which suggests that it may have potential as a pain medication.

In addition to its role in pain signaling pathways, PMPCB is also involved in the regulation of inflammation and cellular stress. It has been shown to play a key role in the regulation of inflammation in various tissues, including the brain and the gastrointestinal tract.

One of the ways that PMPCB is involved in inflammation is through its role in the regulation of the production of pro-inflammatory cytokines. These cytokines, such as TNF-alpha and IL-1, are important for the regulation of immune and inflammatory responses. PMPCB has been shown to inhibit the production of these cytokines, which suggests that it may have potential as an anti-inflammatory drug.

PMPCB is also involved in the regulation of cellular stress, which is a key factor in the development of various diseases, including cancer. It has been shown to play a key role in the regulation of cellular stress in various tissues, including the brain and the gastrointestinal tract.

In conclusion, PMPCB is a protein that is involved in various cellular processes that are important for the regulation of pain signaling pathways, inflammation, and cellular stress. As a result, it is a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of PMPCB in these processes and its potential as a drug.

Protein Name: Peptidase, Mitochondrial Processing Subunit Beta

Functions: Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (PubMed:29576218) (Probable). Preferentially, cleaves after an arginine at position P2 (By similarity). Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis (PubMed:22354088)

The "PMPCB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PMPCB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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