Identification of Proteasome-Converting Enzyme 1B as A Potential Drug Target and Biomarker

Target Name: POC1B

NCBI ID: G282809

POC1B

Identification of Proteasome-Converting Enzyme 1B as A Potential Drug Target and Biomarker

Proteasome-converting enzyme 1B (POC1B) is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the proteasome system, which is responsible for breaking down and degrading proteins. POC1B is expressed in many different cell types, including muscle, nerve, and epithelial cells. It is also expressed in various tissues and organs, including the brain, heart, and liver.

POC1B has been identified as a potential drug target due to its involvement in a variety of cellular processes. One of its main functions is to regulate the activity of other enzymes, such as the 26S ribosome and the chaperone protein HSP70. It is also involved in the degradation of damaged proteins, which is a key aspect of the immune response.

In addition to its role in cellular signaling, POC1B is also of interest as a potential biomarker. The degradation of damaged proteins is a well-established hallmark of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Therefore, it is potentially useful as a diagnostic or therapeutic target in these diseases.

POC1B is also of interest as a potential therapeutic target for a variety of other diseases. For example, it is involved in the regulation of cell signaling pathways that are involved in a variety of cellular processes, including cell growth, differentiation, and inflammation. Therefore , it is potentially useful as a therapeutic target for diseases that are characterized by abnormal cell signaling, such as cancer and autoimmune diseases.

POC1B is also of interest as a potential target for drug discovery due to its well-documented function and its involvement in a variety of cellular processes. The identification of POC1B as a potential drug target has the potential to lead to the development of new therapeutic strategies for a variety of diseases.

POC1B is a protein that is expressed in various tissues throughout the body and is involved in the regulation of cellular processes that are important for normal cellular function. Its involvement in the proteasome system and its potential as a drug target and biomarker make it an attractive target for research and development.

Protein Name: POC1 Centriolar Protein B

Functions: Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567, PubMed:32060285). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation (PubMed:32060285). Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745)

The "POC1B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about POC1B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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