Target Name: PODXL2
NCBI ID: G50512
Review Report on PODXL2 Target / Biomarker Content of Review Report on PODXL2 Target / Biomarker
PODXL2
Other Name(s): Endoglycan | PODLX2 | PDXL2_HUMAN | podocalyxin like 2 | Podocalyxin like 2 | Podocalyxin-like protein 2 | EG | endoglycan

PODXL2: A promising drug target and biomarker for the treatment of various diseases

Podoxylin degrading enzyme 2 (PODXL2) is a protein that plays a crucial role in the regulation of cellular processes, including the degradation of podoxylin, which is a key component of cell membranes. PODXL2 is expressed in various cell types and is involved in various cellular processes, including the regulation of cell adhesion, migration, and the production of intracellular signaling pathways. PODXL2 has also been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. As a result, PODXL2 has emerged as a promising drug target and biomarker for the treatment of these diseases.

Diseases associated with PODXL2

Podoxylin is involved in various cellular processes that are essential for the maintenance of cellular health and homeostasis. The degradation of podoxylin by PODXL2 is critical for the regulation of cellular processes, including cell adhesion, migration, and the production of intracellular signaling pathways. As a result, alterations in PODXL2 expression or function have been implicated in the development and progression of various diseases.

One of the diseases associated with PODXL2 is cancer. PODXL2 has been shown to play a role in the regulation of cell adhesion and migration, which are critical processes for the development of cancer. For instance, studies have shown that PODXL2 is involved in the regulation of cell adhesion and that alterations in PODXL2 expression contribute to the development of various types of cancer. Additionally, PODXL2 has been shown to play a role in the regulation of cell migration, which is a critical process for the development of cancer stem cells.

Another disease associated with PODXL2 is neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. PODXL2 has been shown to play a role in the regulation of the production of intracellular signaling pathways, which are essential for the maintenance of cellular health and homeostasis. Alterations in PODXL2 expression have been implicated in the development and progression of neurodegenerative diseases.

Finally, PODXL2 is also associated with autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. PODXL2 has been shown to play a role in the regulation of the production of intracellular signaling pathways, which are essential for the regulation of immune responses. Alterations in PODXL2 expression have been implicated in the development and progression of autoimmune diseases.

PODXL2 as a drug target

PODXL2 has emerged as a promising drug target due to its involvement in various cellular processes that are essential for the maintenance of cellular health and homeostasis. Various studies have shown that PODXL2 can be targeted by small molecules, including inhibitors of PODXL2-mediated signaling pathways.

One of the potential benefits of targeting PODXL2 is the potential to reduce the production of intracellular signaling pathways, which are essential for the maintenance of cellular health and homeostasis. This can lead to the inhibition of cell growth, apoptosis, and inflammation, which are potential therapeutic benefits for a variety of diseases.

Another potential benefit of targeting PODXL2 is the potential to reduce the production of pro-inflammatory cytokines, which are involved in the regulation of immune responses. This can lead to the inhibition of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

PODXL2 as a biomarker

PODXL2 has also been shown to be a potential biomarker for the development and progression of various diseases. Studies have shown that PODXL2 is involved in the regulation of cell adhesion and

Protein Name: Podocalyxin Like 2

Functions: Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins

The "PODXL2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PODXL2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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