Target Name: GGTLC1
NCBI ID: G92086
Review Report on GGTLC1 Target / Biomarker Content of Review Report on GGTLC1 Target / Biomarker
GGTLC1
Other Name(s): Gamma-glutamyltransferase-like activity 3 | GGT | gamma-glutamyltransferase-like activity 3 | GGTLA4 | DJ831C21.1 | gamma-glutamyltransferase-like activity 4 | gamma-glutamyltransferase-like protein 6 | GGTL1_HUMAN | Gamma-glutamyltransferase-like protein 6 | GGTL6 | Gamma-glutamyltransferase light chain 1, transcript variant A | dJ831C21.1 | gamma-glutamyltransferase light chain 1 | Gamma-glutamyltransferase-like activity 4 | Glutathione hydrolase light chain 1 | Gamma-glutamyl transpeptidase | GGTLA3 | GGTLC1 variant A | gamma-glutamyl transpeptidase | dJ831C21.2 | DJ831C21.2 | Gamma-glutamyltransferase light chain 1

Study on GGTLC1 and Its Associated Diseases

GGTLC1 (Gamma-glutamyltransferase-like activity 1) is a protein that is expressed in various tissues and cell types in the body. It has been shown to play a role in the regulation of cellular processes such as cell adhesion, migration, and invasion. GGTLC1 has also been associated with a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, GGTLC1 has become a focus of research in the scientific community, with a number of studies investigating its potential as a drug target or biomarker.

One of the key features of GGTLC1 is its ability to transfer glutamyl groups to other proteins, leading to the formation of GGTLC1-modified proteins. These modified proteins can interact with a wide range of targets, including other proteins, enzymes, and nucleic acids. One of the most well-studied targets of GGTLC1 is the protein SMAD4, which is a key regulator of cell death and survival.

GGTLC1 has been shown to play a role in the regulation of SMAD4 function. SMAD4 is a transcription factor that has been shown to play a role in a variety of cellular processes, including cell death, cell growth, and tissue repair. to interact with SMAD4 and to regulate its activity. This interaction between GGTLC1 and SMAD4 is important for the regulation of cellular processes that are critical for life, such as cell death and cell growth.

Another target of GGTLC1 is the protein PDGF-BB, which is a key regulator of cell proliferation and differentiation. GGTLC1 has been shown to interact with PDGF-BB and to regulate its activity. This interaction between GGTLC1 and PDGF-BB is important for the regulation of cellular processes that are critical for normal development and growth.

In addition to its role in the regulation of SMAD4 and PDGF-BB, GGTLC1 has also been shown to play a role in the regulation of a variety of other proteins. For example, GGTLC1 has been shown to interact with the protein FBN1, which is involved in blood clotting. This interaction between GGTLC1 and FBN1 is important for the regulation of blood clotting and may have implications for the treatment of bleeding disorders.

GGTLC1 has also been shown to play a role in the regulation of cellular processes that are important for maintaining tissue structure and homeostasis. For example, GGTLC1 has been shown to interact with the protein traf2, which is involved in the regulation of cell adhesion and migration . This interaction between GGTLC1 and traf2 is important for the regulation of tissue structure and homeostasis.

In conclusion, GGTLC1 is a protein that has been shown to play a role in a variety of cellular processes in the body. Its ability to transfer glutamyl groups to other proteins makes it a potential drug target or biomarker. Further research is needed to fully understand the role of GGTLC1 in cellular processes and to develop effective treatments for diseases associated with its dysfunction.

Protein Name: Gamma-glutamyltransferase Light Chain 1

The "GGTLC1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GGTLC1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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