HS3ST4: A Promising Drug Target Or Biomarker (G9951)

Target Name: HS3ST4

NCBI ID: G9951

HS3ST4

HS3ST4: A Promising Drug Target Or Biomarker

HS3ST4, or heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4, is a protein that is expressed in various tissues throughout the body. It is a member of the glycosaminyltransferase family 3 (GAF3) and is responsible for the transfer of D-glucosaminyl groups from the 3-O-sulfotransferase to the N-acetylglucosamine residue of the target protein.

The HS3ST4 gene was identified and its protein was expressed and purified from various sources, including plant, animal, and human tissues. The protein has been shown to have unique properties that make it a promising drug target or biomarker.

One of the key properties of HS3ST4 is its ability to transfer D-glucosaminyl groups from the 3-O-sulfotransferase to the N-acetylglucosamine residue of its target protein. This process is critical for the maintenance of the structure and function of the target protein , and the ability of HS3ST4 to perform this function makes it an attractive target for drugs that are designed to interfere with the structure or function of the target protein.

Another important property of HS3ST4 is its role in the regulation of cellular processes. The protein has been shown to be involved in the regulation of cell adhesion, migration, and the response to stimuli. This makes it an attractive target for drugs that are designed to modulate these processes and may have therapeutic applications in various diseases.

In addition to its unique properties, HS3ST4 is also a good candidate for a biomarker in various diseases. The protein has been shown to be expressed in a variety of tissues and has been used as a marker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. This makes it an attractive target for drugs that are designed to diagnose or treat these diseases.

In conclusion, HS3ST4 is a protein that has unique properties that make it a promising drug target or biomarker. Its ability to transfer D-glucosaminyl groups from the 3-O-sulfotransferase to the N-acetylglucosamine residue of its target protein makes it an attractive target for drugs that are designed to interfere with the structure or function of the target protein. Its role in the regulation of cellular processes and its ability to act as a biomarker for various diseases make it an attractive target for drugs that are designed to diagnose or treat these diseases. Further research is needed to fully understand the properties and potential applications of HS3ST4, but it is clear that it has the potential to be a valuable tool in the fight against various diseases.

Protein Name: Heparan Sulfate-glucosamine 3-sulfotransferase 4

Functions: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity)

The "HS3ST4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HS3ST4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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