ALDH1L1-AS1: A Potential Drug Target and Biomarker (G100874204)

Target Name: ALDH1L1-AS1

NCBI ID: G100874204

ALDH1L1-AS1

Other Name(s): ALDH1L1 antisense RNA 1

ALDH1L1-AS1: A Potential Drug Target and Biomarker

ALDH1L1-AS1, also known as HSP70伪, is a heat shock protein (HSP) that is expressed in various tissues and cells, including the liver, lung, and heart. HSPs are a family of transmembrane proteins that play a critical role in the regulation of cellular homeostasis, and ALDH1L1-AS1 is of particular interest due to its potential as a drug target and biomarker.

The ALDH1 family of proteins is characterized by the presence of a unique N-terminal alpha-helices, which are thought to play a role in the stability and localization of the protein. The alpha-helices are involved in the formation of a disulfide bond, which is important for the stability of the protein and allows it to maintain its functional integrity in various cellular stress conditions.

ALDH1L1-AS1 is a 14kDa protein that is expressed in the liver, lung, and heart. It is highly expressed in the liver, with higher levels observed in thehepatocytes and liver sinusoids compared to the epithelial and immune cells. ALDH1L1-AS1 is also expressed in various other tissues, including the lung, heart, and skeletal muscles.

In terms of its function, ALDH1L1-AS1 is involved in the regulation of cellular homeostasis. It has been shown to play a role in the detoxification of xenobiotics, such as drugs and other harmful substances, which can cause cellular stress and damage. Additionally, ALDH1L1-AS1 has been shown to play a role in the regulation of cellular signaling pathways, including the TGF-β pathway.

As a drug target, ALDH1L1-AS1 is of particular interest due to its potential to modulate cellular stress responses and its involvement in the regulation of cellular signaling pathways. ALDH1L1-AS1 has been shown to interact with a variety of protein partners, including the transcription factor, NF-kappa-B, and the protein, heat shock factor (HSF).

In addition to its potential as a drug target, ALDH1L1-AS1 is also a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. The expression of ALDH1L1-AS1 has been observed in various types of cancer, including breast, lung, and colorectal cancer. Additionally, ALDH1L1-AS1 has been shown to be involved in the regulation of cellular signaling pathways that are involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Conclusion

In conclusion, ALDH1L1-AS1 is a heat shock protein that is expressed in various tissues and cells, including the liver, lung, and heart. It is involved in the regulation of cellular homeostasis and has been shown to play a role in the detoxification of xenobiotics and in the regulation of cellular signaling pathways. As a drug target, ALDH1L1-AS1 is of particular interest due to its potential to modulate cellular stress responses and its involvement in the regulation of cellular signaling pathways. Additionally, ALDH1L1-AS1 is also a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Further research is needed to fully understand the role of ALDH1L1-AS1 in these diseases and to develop effective therapies that target this protein.

Protein Name: ALDH1L1 Antisense RNA 1

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