Target Name: ALDH1L2
NCBI ID: G160428
Review Report on ALDH1L2 Target / Biomarker Content of Review Report on ALDH1L2 Target / Biomarker
ALDH1L2
Other Name(s): Aldehyde dehydrogenase 1L2 (ALDH1L2) | aldehyde dehydrogenase 1 family member L2 | probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2 | DKFZp686M064 | Aldehyde dehydrogenase family 1 member L2 | DKFZp686A16126 | aldehyde dehydrogenase family 1 member L2, mitochondrial | MGC119536 | Probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2 | 10-formyltetrahydrofolate dehydrogenase ALDH1L2 | mitochondrial 10-FTHFDH | MGC119537 | mtFDH | OTTHUMP00000242225 | FLJ38508 | FLJ36769 | AL1L2_HUMAN | Mitochondrial 10-formyltetrahydrofolate dehydrogenase | ALDH1L2 variant 1 | Aldehyde dehydrogenase 1 family member L2, transcript variant 1 | Mitochondrial 10-FTHFDH

ALDH1L2: A Potential Drug Target Or Biomarker

ALDH1L2 (Aldehyde dehydrogenase 1L2) is a gene that encodes a protein known as ALDH1L2. The function of this protein is still not entirely understood, but it is known to be involved in the metabolism of drugs and other harmful substances.

Research has shown that ALDH1L2 is expressed in many different tissues and cells in the body, including the liver, heart, and lungs. It is also expressed in various types of cancer, which suggests that it may be a potential drug target or biomarker for these diseases.

One of the key functions of ALDH1L2 is its ability to metabolize drugs. Many drugs, including chemotherapy drugs, can be metabolized by this protein, which may help to reduce their effectiveness or even cause harm if taken in excess. This is an important reason why ALDH1L2 is a potential drug target or biomarker for drug-resistant cancer.

Another function of ALDH1L2 is its role in the detoxification of harmful substances. Many environmental toxins, such as those found in water, can be metabolized by this protein, which may help to protect the body from harm.

In addition to its role in drug metabolism and detoxification, ALDH1L2 is also involved in the regulation of cellular processes. It has been shown to be involved in the production of reactive oxygen species (ROS), which can cause damage to cells if not properly regulated.

The misfolding of proteins, also known as protein misfolding, is a common occurrence in many diseases, including cancer. ALDH1L2 is also known to be involved in the regulation of protein misfolding, which may be a potential drug target or biomarker for some diseases.

Furthermore, ALDH1L2 is also involved in the regulation of cellular signaling pathways. It has been shown to be involved in the production of various signaling molecules, including insulin and growth factors. This suggests that ALDH1L2 may be a potential drug target or biomarker for diseases that are characterized by abnormal cellular signaling.

In conclusion, ALDH1L2 is a gene that encodes a protein that is involved in a variety of cellular processes in the body. While more research is needed to fully understand its functions, it is already clear that it has the potential to be a drug target or biomarker for many different diseases. As such, it is an attractive target for drug development in the future.

Protein Name: Aldehyde Dehydrogenase 1 Family Member L2

Functions: Mitochondrial 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide

The "ALDH1L2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ALDH1L2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ALDH2 | ALDH3A1 | ALDH3A2 | ALDH3B1 | ALDH3B2 | ALDH4A1 | ALDH5A1 | ALDH6A1 | ALDH7A1 | ALDH8A1 | ALDH9A1 | Aldo-Keto Reductase Family 1 | ALDOA | ALDOAP2 | ALDOB | ALDOC | ALG1 | ALG10 | ALG10B | ALG11 | ALG12 | ALG13 | ALG14 | ALG1L10P | ALG1L13P | ALG1L1P | ALG1L2 | ALG1L5P | ALG1L7P | ALG1L8P | ALG2 | ALG3 | ALG5 | ALG6 | ALG8 | ALG9 | ALK | ALKAL1 | ALKAL2 | Alkaline Phosphatase (ALP) | ALKBH1 | ALKBH2 | ALKBH3 | ALKBH4 | ALKBH5 | ALKBH6 | ALKBH7 | ALKBH8 | ALLC | ALMS1 | ALMS1-IT1 | ALMS1P1 | ALOX12 | ALOX12-AS1 | ALOX12B | ALOX12P2 | ALOX15 | ALOX15B | ALOX15P1 | ALOX15P2 | ALOX5 | ALOX5AP | ALOXE3 | ALPG | Alpha-2 Adrenergic receptors | alpha-6 beta-2 Nicotinic receptor | alpha-Adrenoceptor | alpha-Amylase | alpha-beta T Cell Receptor Complex (TCR) | Alpha-crystallin | alpha-Mannosidase | alpha-Secretase | alpha1-Adrenoceptor | ALPI | ALPK1 | ALPK2 | ALPK3 | ALPL | ALPP | ALS2 | ALS2CL | ALX1 | ALX3 | ALX4 | ALYREF | AMACR | AMBN | AMBP | AMBRA1 | AMD1 | AMD1P2 | AMDHD1 | AMDHD2 | AMELX | AMELY | AMER1 | AMER2 | AMER3 | AMFR | AMH