Calprotectin: A Protein Implicated in Cancer and Inflammation

Target Name: Calprotectin

NCBI ID: P36757

Calprotectin

Calprotectin: A Protein Implicated in Cancer and Inflammation

Calprotectin, also known as Myeloid-related protein 8/14 complex, is a protein that is expressed in the myeloid cells of the human body. It is a member of the myeloid-related protein 8 (MRP8) family, which is a group of non-coding RNAs that are involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation. Calprotectin is a 21-kDa protein that is expressed in various tissues of the body, including blood, bone marrow, and the spleen.

The myeloid-related protein 8 (MRP8) family consists of four isoforms, including MRP8, MRP10, MRP11, and MRP12. These isoforms are involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation. Calprotectin is one of the member of the MRP8 family, which is a group of non-coding RNAs that are involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation.

Calprotectin is a 21-kDa protein that is expressed in various tissues of the body, including blood, bone marrow, and the spleen. It is a member of the myeloid-related protein 8 (MRP8) family, which is a group of non-coding RNAs that are involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation. MRP8 is a key regulator of myeloid development and has been implicated in the development and progression of various diseases, including cancer.

One of the functions of Calprotectin is to regulate the growth and differentiation of myeloid cells. Myeloid cells are a type of white blood cell that play a critical role in the immune system. They are responsible for producing antibodies, which are proteins that help to protect the body against infections and other harmful substances. Myeloid cells also play a key role in the development and maturation of other immune cells, including natural killer cells and T cells.

Calprotectin is also involved in the regulation of inflammation. Myeloid cells are a key source of inflammation in the body, and their overproduction or dysfunction can contribute to the development of various inflammatory diseases, including rheumatoid arthritis, crohn's disease, and multiple sclerosis. Calprotectin has been shown to have anti-inflammatory properties and may be a potential therapeutic target for these diseases.

In addition to its role in cell growth and differentiation, Calprotectin is also involved in the regulation of cellular interactions and signaling. It is a potent signaling molecule that can interact with a variety of cellular signaling pathways, including TGF-beta, NF-kappa-B, and PI3K/AKT. These signaling pathways are involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation.

Calprotectin has also been shown to have potential therapeutic applications in cancer treatment. It has been shown to have anti-tumor properties and may be a potential therapeutic agent for various cancers, including breast, ovarian, and colorectal cancers. Calprotectin has also been shown to enhance the efficacy of chemotherapy by inhibiting the activity of cancer cells' biomarkers, such as the protein Ku70.

In conclusion, Calprotectin is a protein that is expressed in various tissues of the body and is involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation. It is a member of the myeloid-related protein 8 (MRP8) family and has been implicated in the development and progression of various diseases, including cancer. Its anti-inflammatory and anti-tumor properties make it a potential therapeutic agent for various cancers. Further research is needed to fully understand the role of Calprotectin in

Protein Name: Calprotectin

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•   general information;
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•   expression level;
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