KLK11: A Protein Regulator of Inflammation and Cell Adhesion (G11012)

Target Name: KLK11

NCBI ID: G11012

KLK11

KLK11: A Protein Regulator of Inflammation and Cell Adhesion

KLK11, also known as hK11, is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a member of the Kallikrein family, which includes several other proteins that play important roles in the immune system and inflammation.

One of the functions of KLK11 is to regulate the production of inflammatory cytokines, which are proteins that play a key role in the inflammatory response. These cytokines can cause a range of symptoms, including pain, inflammation, and damage to tissues. By regulating the production of these cytokines, KLK11 helps to maintain a balance between the immune system and the body's tissues, which is important for maintaining overall health.

Another function of KLK11 is to regulate the production of regulatory proteins, which are proteins that help to regulate the activity of other proteins. These regulatory proteins can include factors that promote or inhibit the activity of other proteins, and they play a key role in maintaining the balance between different cell types and tissues.

KLK11 is also involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. This is important for the development and maintenance of tissues and organs, and it is also involved in the regulation of the immune response.

In addition to its functions in regulation of cytokines, regulatory proteins, and cell adhesion, KLK11 is also involved in the regulation of inflammation. It has been shown to play a key role in the regulation of inflammation in the gut, and it is thought to contribute to the development of inflammatory bowel disease (IBD) and other inflammatory disorders.

KLK11 is also a potential drug target, as it has been shown to play a role in the development of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Studies have shown that KLK11 is involved in the regulation of the immune response, and that it can contribute to the development and progression of these diseases.

In conclusion, KLK11 is a protein that plays a critical role in the regulation of various functions in the body, including inflammation, cell adhesion, and the immune response. It is also a potential drug target, and further research is needed to better understand its role in the development and treatment of various diseases.

Protein Name: Kallikrein Related Peptidase 11

Functions: Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues

The "KLK11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLK11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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