KLRB1: A Protein Involved in A Variety of Cellular Processes (G3820)

Target Name: KLRB1

NCBI ID: G3820

KLRB1

KLRB1: A Protein Involved in A Variety of Cellular Processes

KLRB1 (Kallikrein-related molecule 1) is a protein that is expressed in a variety of cell types, including epithelial, hematopoietic, and nervous cells. It is a 25kDa protein that is characterized by its ability to recognize and bind to various carbohydrates, including bacterial and viral peptides. KLRB1 is also known as C-type lectin, a type of carbohydrate recognition protein that is expressed in many different cell types.

KLRB1 is expressed in a variety of tissues and cells throughout the body, including the skin, hair, nails, mouth, and gut. It is also expressed in the placenta, which suggests that it may be involved in fetal development and growth. KLRB1 is also expressed in the liver, where it has been shown to play a role in the regulation of inflammation and metabolism.

One of the unique features of KLRB1 is its ability to recognize and bind to carbohydrates that are derived from bacteria and viruses. This is accomplished through the use of its carbohydrate-binding domain, which is composed of a parallel beta-sheet structure that is characteristic of this type of protein. The carbohydrate-binding domain is responsible for the recognition of carbohydrates, which allows KLRB1 to interact with and bind to a wide variety of different molecules.

KLRB1 has also been shown to play a role in the regulation of cellular processes, including cell signaling, cell adhesion, and cell migration. For example, studies have shown that KLRB1 can interact with the protein FAK (focal adhesion kinase) and that this interaction may play a role in the regulation of cell migration. Additionally, KLRB1 has been shown to interact with the protein PDGFR (Pyruvate-dependent Growth and divide gene 1), which is involved in the regulation of cell growth and proliferation.

KLRB1 is also involved in the regulation of cellular responses to stress, including the regulation of inflammation and cellular stress responses. Studies have shown that KLRB1 can interact with the protein NF-kappa-B (nuclear factor kappa B), which is involved in the regulation of inflammation and stress responses. Additionally, KLRB1 has been shown to interact with the protein p62 (PAX62), which is involved in the regulation of cellular stress responses.

KLRB1 is also involved in the regulation of cellular processes that are important for overall health and wellness, including the regulation of inflammation and aging. Studies have shown that KLRB1 can interact with the protein TLR2 (Toll-like receptor 2), which is involved in the regulation of cellular responses to bacterial and viral pathogens. Additionally, KLRB1 has been shown to interact with the protein NOD2 (NOD2 receptor), which is involved in the regulation of cellular responses to bacterial and viral pathogens.

KLRB1 is also a potential drug target and may be a biomarker for a variety of diseases. For example, studies have shown that KLRB1 is involved in the regulation of cellular responses to bacterial and viral pathogens, which makes it a potential target for the development of new antibiotics. Additionally, KLRB1 has been shown to be involved in the regulation of cellular processes that are important for overall health and wellness, which makes it a potential target for the development of new therapies for a variety of diseases.

In conclusion, KLRB1 is a protein that is expressed in a variety of cell types throughout the body and is involved in a wide range of cellular processes that are important for overall health and wellness. Its ability to recognize and bind to various carbohydrates, including bacterial and viral peptides, makes it a potential drug target and may make it a useful biomarker for the development of new therapies for a variety of diseases. Further research is needed to fully understand the role of KLRB1 in cellular processes and its potential as a drug target.

Protein Name: Killer Cell Lectin Like Receptor B1

Functions: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells

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•   general information;
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•   protein biological mechanisms;
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•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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