CHST10: A Protein Involved in Tissue Development and Maintenance

Target Name: CHST10

NCBI ID: G9486

CHST10

CHST10: A Protein Involved in Tissue Development and Maintenance

CHST10, also known as HNK1ST, is a protein that is expressed in various tissues throughout the body. It is a member of the homeobox gene family, which is a group of genes that are involved in the development and maintenance of normal tissues and organs. CHST10 is specifically known for its role in cell division and has been studied for its potential as a drug target or biomarker.

One of the key functions of CHST10 is its role in cell division. During cell division, CHST10 helps to ensure that the cell divides correctly and that the resulting cells are compatible with the surrounding tissue. This is important for the development and maintenance of tissues and organs, as well as for the growth and development of the entire organism.

Another function of CHST10 is its role in cell signaling. CHST10 is involved in a variety of signaling pathways, including those that regulate cell growth, differentiation, and survival. It has been shown to play a role in the regulation of cell proliferation and has been shown to interact with a variety of signaling molecules, including TGF-β1, a key regulator of cell growth and differentiation.

In addition to its role in cell division and signaling, CHST10 is also involved in the regulation of cell adhesion. CHST10 is a member of the cadherin gene family, which is responsible for the regulation of cell adhesion and the development of tissues and organs. This is important for the development and maintenance of tissues and organs, as well as for the proper functioning of the organism as a whole.

CHST10 has also been shown to play a role in the regulation of cell migration. During cell migration, CHST10 helps to ensure that the cell moves through the tissue in a proper and controlled manner and that it reaches its destination. This is important for the development and maintenance of tissues and organs, as well as for the proper functioning of the organism.

In conclusion, CHST10 is a protein that is involved in a variety of important functions in the development and maintenance of tissues and organs. Its role in cell division, signaling, adhesion, and migration is just a few examples of the many functions that CHST10 plays. As a result, CHST10 is a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of CHST10 in the development and maintenance of tissues and organs, as well as its potential as a drug or biomarker.

Protein Name: Carbohydrate Sulfotransferase 10

Functions: Catalyzes the transfer of sulfate from 3'-phosphoadenylyl sulfate (PAPS) to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure 3-O-sulfo-beta-D-GlcA-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-R, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis (PubMed:9478973). Sulfates terminal glucuronyl residue of the laminin globular (LG)-domain binding epitope on DAG1/alpha-dystroglycan and prevents further polymerization by LARGE1 glycosyltransferase. Likely defines the chain length of LG epitope, confering binding specificity to extracellular matrix components (PubMed:32149355). Plays a role in down-regulating the steroid hormones. Sulfates glucuronidated estrogens and androgens with an impact in hormone cycle and fertility. Has a preference for glucuronyl moiety at the 3-hydroxyl group of a sterol ring rather than the 17-hydroxyl group, showing high catalytic efficiency for 17beta-estradiol 3-O-(beta-D-glucuronate) and dehydroepiandrosterone 3-O-(beta-D-glucuronate) hormones (PubMed:23269668)

The "CHST10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CHST10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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