RBP7: A Potential Drug Target for Cell Signaling and Disease (G116362)

Target Name: RBP7

NCBI ID: G116362

RBP7

RBP7: A Potential Drug Target for Cell Signaling and Disease

RBP7 (Cellular retinoic acid-binding protein 7) is a protein that is expressed in various tissues throughout the body, including the retina, liver, and heart. It is a member of the superfamily of transmembrane proteins, which means that it spans the cell membrane and is associated with various intracellular signaling pathways. One of the most significant functions of RBP7 is its role in cell signaling, particularly in the regulation of cell proliferation and differentiation.

Despite the importance of RBP7 in cellular signaling, its role in the development and progression of various diseases remains poorly understood. However, recent studies have identified RBP7 as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders . In this article, we will explore the role of RBP7 in cell signaling and its potential as a drug target.

Structure and Function

The structure of RBP7 is unique, as it is a member of the superfamily of transmembrane proteins. It consists of 111 amino acid residues and has a calculated molecular weight of 13.9 kDa. RBP7 has a unique feature, known as a \"tail\" region, which is located at its C-terminus. This region is composed of a series of secondary structure elements, including a long coiled-coil and a protein-protein interaction domain.

The function of RBP7 is closely tied to its unique structure. RBP7 functions as a receptor for cellular retinoic acid, which is a signaling molecule that plays a crucial role in the regulation of cell proliferation and differentiation. Retinoic acid is a fatty acid that is derived from the vitamin A. It is involved in a wide range of cellular processes, including cell signaling, cell division, and tissue growth.

In addition to its role in cell signaling, RBP7 is also recognized as a potential drug target. Its unique structure and the various functions that it is involved in make it an attractive target for small molecules. In fact, several studies have identified RBP7 as a potential drug candidate for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Drug Target Potential

RBP7 has been identified as a potential drug target due to its unique structure and the various functions that it is involved in. One of the key reasons for its potential as a drug target is its involvement in cell signaling. As mentioned earlier, RBP7 is a receptor for cellular retinoic acid, which plays a crucial role in the regulation of cell proliferation and differentiation. Therefore, small molecules that can modulate cellular retinoic acid signaling may be effective in targeting RBP7 and its downstream targets.

Another reason why RBP7 is a potential drug target is its involvement in the regulation of cell adhesion. RBP7 is a protein that is involved in the regulation of cell-cell adhesion, which is a critical process that is involved in the development and maintenance of tissues and organs. Therefore, small molecules that can modulate cell-cell adhesion may be effective in targeting RBP7 and its downstream targets.

In addition to its involvement in cell signaling and cell adhesion, RBP7 is also involved in the regulation of cell cycle progression. As mentioned earlier, RBP7 is a regulator of cell cycle progression, which is the process by which cells grow, divide, and replicate themselves. Therefore, small molecules that can modulate cell cycle progression may be effective in targeting RBP7 and its downstream targets.

Targeting RBP7

Several studies have identified potential small molecules that can modulate cellular retinoic acid signaling, cell adhesion, and cell cycle progression. These small molecules include inhibitors of retinoic acid receptors, inhibitors of the protein

Protein Name: Retinol Binding Protein 7

Functions: Intracellular transport of retinol

The "RBP7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RBP7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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