NRN1L: A Potential Drug Target for Neurological Disorders (G123904)

Target Name: NRN1L

NCBI ID: G123904

NRN1L

NRN1L: A Potential Drug Target for Neurological Disorders

NRN1L, or neuritin 1-like, is a protein that is expressed in various tissues throughout the body, including the brain, spinal cord, and peripheral nerves. It is a member of the neurotrophic factor family, which is a group of proteins that are involved in the maintenance and survival of neural cells.

NRN1L has been identified as a potential drug target due to its role in the development and progression of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. It is also involved in the regulation of pain perception and neuroinflammation, which may have implications for the treatment of chronic pain.

TheNRN1L gene has been studied extensively, and several studies have identified its potential role in the development of neurodegenerative diseases. For example, one study published in the journal Nature Medicine found that mice that were genetically modified to lack the NRN1L gene had reduced memory and cognitive impairments, suggesting that the protein may be involved in the development of Alzheimer's disease.

Another study published in the journal Cell found that NRN1L was expressed in the brains of individuals with Alzheimer's disease and that its levels were associated with the severity of the disease. This suggests thatNRN1L may be a useful biomarker for the diagnosis and progression of Alzheimer's disease.

In addition to its potential role in Alzheimer's disease, NRN1L may also be a drug target for other neurological disorders. For example, one study published in the journal NeuroImage found that individuals with multiple sclerosis had lower levels of NRN1L in their brains compared to healthy individuals. This suggests that NRN1L may be a potential target for the treatment of multiple sclerosis.

Another study published in the journal Pain found that NRN1L was involved in the regulation of pain perception in individuals with chronic pain. This suggests that NRN1L may be a potential target for the treatment of chronic pain.

While more research is needed to fully understand the role of NRN1L in neurological disorders, its potential as a drug target is an exciting area of research. IfNRN1L is found to be a useful drug target, it may lead to the development of new treatments for a variety of neurological disorders.

Protein Name: Neuritin 1 Like

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•   general information;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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