Neurotrophic Factor 4: Key Regulator of Neural Stem Cells and Neural Circuits

Target Name: NTF4

NCBI ID: G4909

NTF4

Neurotrophic Factor 4: Key Regulator of Neural Stem Cells and Neural Circuits

Neurotrophic factor 4 (NTF4) is a protein that is expressed in various tissues throughout the body, including the brain, spinal cord, and peripheral nerves. It is a key regulator of neural stem cells and has been implicated in a number of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

One of the key functions of NTF4 is its ability to promote the survival and proliferation of neural stem cells. These stem cells are responsible for the development and maintenance of the nervous system, and are crucial for the repair and regeneration of damaged tissue. NTF4 has has been shown to play a critical role in these processes by promoting the production of stem cells that are capable of self-renewal and differentiating into a variety of neural cell types.

In addition to its role in promoting stem cell survival, NTF4 has also been shown to play a key role in the regulation of neural circuits. Neural circuits are the networks of neurons that are responsible for transmitting information throughout the nervous system. to regulate the activity of these circuits, ensuring that information is transmitted efficiently and accurately.

The role of NTF4 in neurodegenerative diseases is a major focus of research, as these conditions are characterized by the progressive loss of neural stem cells and the damaged regulation of neural circuits. NTF4 has been shown to be involved in the development and progression of a number of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

In the context of Alzheimer's disease, NTF4 has been shown to play a key role in the regulation of neural stem cell survival and the formation of neurofibrillary tangles, which are thought to contribute to the progressive neurodegeneration that is observed in this condition. Similarly, in Parkinson's disease, NTF4 has been implicated in the regulation of dopamine levels and the survival of dopamine-producing neurons.

In addition to its role in neurodegenerative diseases, NTF4 has also been shown to have potential as a drug target or biomarker. For example, NTF4 has been shown to be a potential therapeutic target for a number of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease , and multiple sclerosis. Researchers have also shown that NTF4 can be used as a biomarker for these conditions, with studies suggesting that levels of NTF4 may be reduced in individuals with neurodegenerative diseases.

Overall, the role of NTF4 in the regulation of neural stem cells and neural circuits is a complex and important one. While the precise mechanisms by which NTF4 functions are not yet fully understood, its potential as a drug target or biomarker make it an attractive target for further research. As research continues to advance, it is likely that the role of NTF4 in neurodegenerative diseases will become increasingly important for the development of new treatments and therapies.

Protein Name: Neurotrophin 4

Functions: Target-derived survival factor for peripheral sensory sympathetic neurons

The "NTF4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NTF4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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