NBP1: A Potential Drug Target for Diseases (G4682)

Target Name: NUBP1

NCBI ID: G4682

NUBP1

NBP1: A Potential Drug Target for Diseases

The Nucleotide-Binding Protein 1 (NBP1) is a protein that is expressed in various cell types of the human body. It is a member of the nucleotide-binding protein family, which includes proteins that interact with nucleotides such as DNA, RNA, and FBN1. NBP1 is highly expressed in the brain and is involved in a number of cellular processes, including cell signaling, chromatin structure remodeling, and inflammation.

One of the most promising aspects of NBP1 is its potential as a drug target. The NBP1 gene has been shown to be involved in a number of diseases, including neurodegenerative disorders, cancer, and autoimmune diseases. Additionally, NBP1 has been shown to play a role in the development of certain diseases, such as heart disease and diabetes.

One of the potential mechanisms by which NBP1 may be involved in the development and progression of certain diseases is through its role in cell signaling. NBP1 has been shown to play a role in regulating the activity of various signaling pathways, including the TGF-β pathway . This pathway is involved in a number of cellular processes, including cell growth, differentiation, and inflammation. NBP1 has been shown to play a negative role in the regulation of the TGF-β pathway, which may contribute to its potential as a drug target.

Another potential mechanism by which NBP1 may be involved in the development and progression of certain diseases is through its role in chromatin structure remodeling. NBP1 has been shown to play a role in the regulation of the organization and dynamics of chromatin, which is important for the regulation of gene expression and the development of various diseases.

In addition to its potential role in cell signaling and chromatin structure, NBP1 has also been shown to play a role in inflammation. NBP1 has been shown to be involved in the regulation of the immune response, which is important for the development and progression of certain diseases. Additionally, NBP1 has been shown to play a role in the regulation of inflammation-related signaling pathways, which may contribute to its potential as a drug target in diseases that are characterized by inflammation.

Overall, NBP1 is a protein that has the potential to be a drug target due to its involvement in a number of cellular processes that are important for the development and progression of various diseases. Further research is needed to fully understand the role of NBP1 in these processes and to determine its potential as a drug target.

Protein Name: NUBP Iron-sulfur Cluster Assembly Factor 1, Cytosolic

Functions: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity)

The "NUBP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUBP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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