Target Name: NUB1
NCBI ID: G51667
Review Report on NUB1 Target / Biomarker Content of Review Report on NUB1 Target / Biomarker
NUB1
Other Name(s): NUB1_HUMAN | NUB1L | renal carcinoma antigen NY-REN-18 | NEDD8 ultimate buster 1 | NEDD8 ultimate buster-1 | BS4 | NY-REN-18 antigen | Renal carcinoma antigen NY-REN-18 | Negative regulator of ubiquitin-like proteins 1 | negative regulator of ubiquitin like proteins 1 | NYREN18

Understanding NUB1: A Protein Implicated in Cancer, Neurodegenerative Diseases

NUB1 is a protein that is expressed in a variety of tissues throughout the body, including the nervous system, endocrine system, and immune system. It is a key regulator of cell division and has been implicated in a number of cellular processes, including the regulation of stem cell proliferation and the development of cancer.

Recent studies have identified NUB1 as a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. NUB1 has also been shown to be involved in a number of cellular processes that are associated with aging, such as the regulation of cellular senescence and the role in the development of age-related diseases.

One of the key challenges in studying NUB1 is its complex structure and the fact that it is expressed in a variety of tissues. NUB1 is a transmembrane protein that is expressed in the cytoplasm of cells, meaning that it is not trapped inside the cell's nucleus. This makes it difficult to study, as the effects of NUB1 on cellular processes can be difficult to separate from those of the cell's other components.

However, researchers have made significant progress in understanding the biology of NUB1 and its role in various diseases. One of the most promising areas of research is the study of NUB1's role in cancer. NUB1 has been shown to be involved in the regulation of cell division and has been implicated in the development of a variety of cancers, including breast, ovarian, and prostate cancer.

In addition to its role in cancer, NUB1 is also thought to be involved in a number of other cellular processes that are associated with aging. For example, NUB1 has been shown to be involved in the regulation of cellular senescence, which is the process by which cells age and eventually die. It is also thought to play a role in the development of age-related diseases, such as Alzheimer's disease and other forms of dementia.

Another promising area of research is the study of NUB1's role in neurodegenerative diseases. NUB1 has been implicated in the development and progression of a variety of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

In addition to its role in these diseases, NUB1 is also thought to be involved in a number of other cellular processes that are important for cellular function. For example, it is involved in the regulation of the immune system, which is important for fighting off infections and diseases. It is also involved in the regulation of the production of hormones, which is important for maintaining cellular balance and regulating a variety of physiological processes.

Overall, NUB1 is a protein that has the potential to be a drug target for a variety of diseases. Its complex structure and the fact that it is expressed in a variety of tissues make it difficult to study, but recent advances in our understanding of its biology have outlined a promising path for the future of research into this protein.

Protein Name: Negative Regulator Of Ubiquitin Like Proteins 1

Functions: Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2

The "NUB1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUB1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NUBP1 | NUBP2 | NUBPL | NUCB1 | NUCB2 | NUCKS1 | Nuclear factor interleukin-3-regulated protein-like | Nuclear factor of activated T-cells | Nuclear Pore Complex | Nuclear Receptor ROR | Nuclear transcription factor Y | Nucleoside Diphosphate Kinase (NDK) | Nucleosome Remodeling and Deacetylase (NuRD) Complex | Nucleosome-remodeling factor complex (NURF) | NUDC | NUDCD1 | NUDCD2 | NUDCD3 | NUDCP2 | NUDT1 | NUDT10 | NUDT11 | NUDT12 | NUDT13 | NUDT14 | NUDT15 | NUDT15P1 | NUDT16 | NUDT16-DT | NUDT16L1 | NUDT16L2P | NUDT17 | NUDT18 | NUDT19 | NUDT2 | NUDT21 | NUDT22 | NUDT3 | NUDT4 | NUDT4B | NUDT4P2 | NUDT5 | NUDT6 | NUDT7 | NUDT8 | NUDT9 | NUDT9P1 | NUF2 | NUFIP1 | NUFIP2 | NUGGC | NUMA1 | NUMB | NUMBL | NUP107 | Nup107-160 complex | NUP133 | NUP153 | NUP155 | NUP160 | NUP188 | NUP205 | NUP210 | NUP210L | NUP210P1 | NUP210P2 | NUP214 | NUP35 | NUP37 | NUP42 | NUP43 | NUP50 | NUP50-DT | NUP54 | NUP58 | NUP62 | NUP62CL | NUP85 | NUP88 | NUP93 | NUP98 | NUPR1 | NUPR2 | NUS1 | NUS1P1 | NUS1P3 | NUSAP1 | NUTF2 | NUTF2P4 | NUTM1 | NUTM2A | NUTM2A-AS1 | NUTM2B | NUTM2B-AS1 | NUTM2D | NUTM2E | NUTM2F | NUTM2G | NVL | NWD1