Target Name: NRXN2
NCBI ID: G9379
Review Report on NRXN2 Target / Biomarker Content of Review Report on NRXN2 Target / Biomarker
NRXN2
Other Name(s): NRX2A_HUMAN | Neurexin 2, transcript variant beta | NRX2B_HUMAN | NRXN2 variant beta | Neurexin-2 (isoform alpha-2) | Neurexin-2 | Neurexin 2, transcript variant alpha-1 | Neurexin II | Neurexin-2-beta | NRXN2 variant alpha-2 | neurexin 2 | Neurexin 2, transcript variant alpha-2 | FLJ40892 | NRXN2 variant alpha-1 | Neurexin 2 | Neurexin-2-beta (isoform beta) | Neurexin II-alpha | Neurexin-2 (isoform alpha-1) | KIAA0921 | Neurexin II-beta | neurexin II | Neurexin-2-alpha

NRXN2: Potential Drug Target and Biomarker for Neurological Disorders

NRXN2 (NRX2A_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and liver. Its function is not well understood, but it is known to be involved in several cellular processes that are important for maintaining tissue health and function. As a drug target or biomarker, NRXN2 may be targeted by researchers and clinicians to treat a variety of diseases.

The NRXN2 gene is located on chromosome 6p21.2 and has been annotated as a potential gene for neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. It is thought to be involved in the development and progression of these conditions, as well as other neurological disorders.

NRXN2 is expressed in a variety of tissues and cells in the body, including the brain, heart, kidneys, and liver. It is highly expressed in the brain, where it is found in the basal ganglia, a network of neurons that are responsible for controlling movement and other motor functions. It is also expressed in the heart, where it is involved in the regulation of contractions and the maintenance of heart rate.

In addition to its expression in the brain and heart, NRXN2 is also expressed in other tissues and cells. It is found in the kidneys, where it may be involved in the regulation of water and electrolyte balance. It is also expressed in the liver, where it may be involved in the metabolism and detoxification of harmful substances.

The exact function of NRXN2 is not well understood, but it is thought to be involved in several cellular processes that are important for maintaining tissue health and function. It is involved in the regulation of the growth and differentiation of cells, as well as the maintenance of the cytoskeleton. It may also be involved in the regulation of signaling pathways that control cell behavior, such as the PI3K/Akt signaling pathway.

NRXN2 is a potential drug target or biomarker for a variety of neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. These conditions are characterized by the progressive loss of brain cells, which can lead to a range of symptoms, including memory loss, difficulty with movement, and changes in mood and behavior.

In addition to its potential as a drug target or biomarker, NRXN2 may also be used as a diagnostic tool for these conditions. The expression of NRXN2 in various tissues and cells may be affected by the progression of these conditions, which could provide a sensitive and reliable indicator of the presence of these disorders.

Overall, NRXN2 is a protein that is expressed in various tissues and cells in the human body. Its function is not well understood, but it is thought to be involved in several cellular processes that are important for maintaining tissue health and function. As a drug target or biomarker, NRXN2 may be targeted by researchers and clinicians to treat a variety of diseases.

Protein Name: Neurexin 2

Functions: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling

The "NRXN2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NRXN2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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