Identifying Potential Drug Targets for NT5DC4 (G284958)

Target Name: NT5DC4

NCBI ID: G284958

NT5DC4

Other Name(s): 5'-nucleotidase domain containing 4 | NT5D4_HUMAN | 5'-nucleotidase domain-containing protein 4

Identifying Potential Drug Targets for NT5DC4

Nucleotidase is an enzyme that is involved in the DNA replication process in eukaryotic cells. It is a crucial enzyme that helps ensure the continuation of genetic information from one generation to the next. The 5'-nucleotidase domain containing 4 (NT5DC4) is a protein that is expressed in various cell types and is involved in the process of DNA replication. This protein has been identified as a potential drug target or biomarker, and this article will discuss its properties, functions, and potential applications in the field of medicine.

Properties of NT5DC4

NT5DC4 is a 25 kDa protein that is composed of 118 amino acid residues. It has a characteristic molecular weight of 185.9 kDa and a pI of 6.5. The protein has a linear molecular structure and a calculated molecular weight of 185.9 kDa. It has a single gene that is located on chromosome 18q21.

Function of NT5DC4

NT5DC4 is a nucleotidase enzyme that is involved in the 5' end of double-stranded DNA. This enzyme has two main functions:

1. DNA replication: NT5DC4 is involved in the replication of double-stranded DNA at the 5' end. It uses a specific set of primers to initiate the replication process and is required for the production of new double-stranded DNA.
2. DNA damage repair: NT5DC4 is also involved in the repair of DNA damage at the 5' end. It has been shown to play a role in the repair of DNA double-strand breaks and can also participate in the repair of single-stranded DNA breaks.

Potential Applications

NT5DC4 has been identified as a potential drug target or biomarker due to its involvement in DNA replication and repair processes. If approved, NT5DC4 could be used as a treatment for various diseases that are caused by DNA damage, such as cancer, neurodegenerative diseases, and genetic disorders.

One of the main advantages of NT5DC4 is its small size, which makes it a potential drug candidate. The small size of NT5DC4 also makes it easier to target and manipulate the protein.

Another potential application of NT5DC4 is its role in DNA replication and repair. The replication and repair processes of DNA are critical for the growth and survival of cells, andNT5DC4 plays a crucial role in these processes. Therefore,NT5DC4 could be used as a biomarker to monitor the effectiveness of drugs that are designed to repair or replicate damaged DNA.

Conclusion

In conclusion, NT5DC4 is a protein that is involved in the process of DNA replication and repair. It has been identified as a potential drug target or biomarker, due to its small size and its involvement in critical processes for cell growth and survival. Further research is needed to fully understand the properties and functions of NT5DC4, and to determine its potential applications in the field of medicine.

Protein Name: 5'-nucleotidase Domain Containing 4

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