TSACC (Tumor-associated Extracellular Active Characterization) Complex in Cancer: A Potential Drug Target and Biomarker

Target Name: TSACC

NCBI ID: G128229

TSACC

TSACC (Tumor-associated Extracellular Active Characterization) Complex in Cancer: A Potential Drug Target and Biomarker

Abstract:

The TSACC (Tumor-associated Extracellular Active Characterization) complex has been identified as a promising drug target and biomarker in cancer. It plays a crucial role in the regulation of cell adhesion, migration, and invasion, and its dysregulation has been implicated in the development and progression of many types of cancer. This article will discuss the TSACC system, its potential as a drug target, and its role as a biomarker for cancer diagnosis and treatment.

Introduction:

Cancer is a leading cause of morbidity and mortality worldwide, with over 20 million new cases and 5.5 million deaths in 2019, according to the World Health Organization (WHO). The development and progression of cancer is a complex process that involves the interplay of multiple genetic and epigenetic factors. One of the key factors that have been identified in this process is the regulation of cell adhesion and migration, which are critical for the growth, survival, and progression of cancer cells.

The TSACC (Tumor-associated Extracellular Active Characterization) complex has been identified as a promising drug target and biomarker in cancer. The TSACC system is a multi-component protein complex that is involved in the regulation of cell adhesion, migration, and invasion. It Consists of several key components, including TSACC1, TSACC2, TSACC3, TSACC4, TSACC5, TSACC6, TSACC7, TSACC8, TSACC9, TSACC10, and TSACC11.

The TSACC system plays a crucial role in the regulation of cell adhesion and migration by controlling the interactions between adhesion molecules and the cytoskeleton. It does this by regulating the distribution and activity of adhesion molecules, such as cadherins and immunoglobulin-like cell adhesion molecules ( Ig-CAMs), as well as the cytoskeleton, including the protein tau.

TSACC has also been shown to be involved in the regulation of cell migration and invasion. It does this by regulating the activities of the myosin ATPase, which is a key component of the cytoskeleton, and the RhoA GTPase, which is involved in cell migration and invasion.

Potential as a drug target:

The TSACC system has been identified as a promising drug target for cancer because of its involvement in the regulation of cell adhesion, migration, and invasion. By targeting the TSACC system with drugs that can modulate its activity, researchers hope to develop new treatments for a variety of cancer types.

One of the key challenges in developing drugs that target the TSACC system is the complexity of its downstream signaling pathways. The TSACC system is involved in the regulation of multiple cellular processes, including cell adhesion, migration, and invasion, and it is likely that multiple signaling pathways are involved in its function. This makes it difficult to identify small molecules that can modulate its activity and develop effective treatments.

However, researchers have identified several small molecules that have shown promise in modulating the TSACC system. These molecules include inhibitors of the protein tyrosine kinase (PTK), which is involved in the regulation of cell growth and survival, as well as inhibitors of the protein kinase B (PKB), which is involved in cell adhesion and migration.

In addition to inhibitors of PTK and PKB, researchers have also identified small molecules that can modulate the activity of the TSACC system by interacting with its components. These molecules include inhibitors of the protein tyrosine phosphatase (PTP), which is involved in the regulation of protein tyrosination, as well as inhibitors of the protein kinase domain-containing (PKD) protein, which is involved in the regulation of

Protein Name: TSSK6 Activating Cochaperone

Functions: Co-chaperone that facilitates HSP-mediated activation of TSSK6

The "TSACC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TSACC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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