EIF3KP1: A Potential Drug Target and Biomarker (G134505)

Target Name: EIF3KP1

NCBI ID: G134505

EIF3KP1

Other Name(s): eukaryotic translation initiation factor 3 subunit K pseudogene 1 | Eukaryotic translation initiation factor 3 subunit K pseudogene 1

EIF3KP1: A Potential Drug Target and Biomarker

Eukaryotic translation initiation factor 3 (EIF3KP1) is a protein that plays a crucial role in the process of translation of mRNAs from the DNA to protein in eukaryotic cells. It is a key component of the machinery that enables the efficient translation of gene information from the DNA to proteins that are essential for cellular function and growth.

Recent studies have identified EIF3KP1 as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and developmental disorders. This is due to its involvement in the translation of several key proteins that are implicated in these diseases, as well as its potential role in modulating the levels of these proteins in the cells.

One of the key functions of EIF3KP1 is its role in the initiation of the translation process. It is a protein that forms a complex with the small nuclear RNA (snRNA) molecule translocation complex, which is responsible for bringing the mRNA to the ribosome for translation . By interacting with the snRNA molecule, EIF3KP1 helps to ensure that the mRNA is properly translated into protein.

In addition to its role in the initiation of translation, EIF3KP1 is also involved in the regulation of translation efficiency. Studies have shown that EIF3KP1 can interact with several different proteins that are involved in the regulation of translation, including the protein translocation factor (PTF) and the RNA-binding protein (RBP) complex. These interactions can alter the structure and stability of these proteins, which in turn can affect the efficiency of translation.

The identification of EIF3KP1 as a potential drug target and biomarker has important implications for the development of new treatments for a variety of diseases. For example, studies have shown that EIF3KP1 is highly expressed in various types of cancer, and that it is involved in the regulation of the growth and survival of cancer cells. Therefore, targeting EIF3KP1 with small molecules or other therapeutic agents may be a promising strategy for the treatment of cancer.

In addition to its potential as a cancer drug, EIF3KP1 has also been identified as a potential biomarker for a variety of other diseases. For example, studies have shown that EIF3KP1 is involved in the regulation of the translation of several key proteins that are implicated in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Therefore, targeting EIF3KP1 with therapeutic agents that can modulate its activity may be a promising strategy for the treatment of these diseases.

Another potential application of EIF3KP1 as a drug target and biomarker is its role in the regulation of cellular processes that are important for overall health and function. For example, EIF3KP1 is involved in the regulation of the levels of several key proteins that are involved in cell signaling and metabolism, including the protein kinase B (PKB) and the transcription factor Spec1 (SP1). These proteins play important roles in the regulation of cellular processes that are essential for proper growth, development, and function. Therefore, modulating the activity of EIF3KP1 may be a promising strategy for the treatment of a variety of cellular processes that are involved in health and disease.

In conclusion, EIF3KP1 is a protein that plays a crucial role in the process of translation of mRNAs from the DNA to protein in eukaryotic cells. Its involvement in the initiation and regulation of translation makes it a potential drug target and biomarker for a variety of diseases . Further studies are needed to fully understand the role of EIF3KP1 in cellular processes and to develop effective treatments based on its properties.

Protein Name: Eukaryotic Translation Initiation Factor 3 Subunit K Pseudogene 1

The "EIF3KP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EIF3KP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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