ELOVL4: A Potential Drug Target and Biomarker (G6785)

Target Name: ELOVL4

NCBI ID: G6785

ELOVL4

ELOVL4: A Potential Drug Target and Biomarker

Elongation of very long chain fatty acids (ELOVL4) is a process that involves the production of long-chain fatty acids from shorter ones. Fatty acids are essential for the maintenance of cellular life, and their levels are often affected by various factors, including diet, metabolism, and health conditions. Elongation of very long chain fatty acids is a post-translational modification that involves the addition of four amino acids to the end of a protein sequence, resulting in a protein with a longer overall length.

ELOVL4 has been identified as a potential drug target and biomarker in various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. In this article, we will discuss the potential mechanisms by which ELOVL4 can be targeted as a drug and its potential as a biomarker for disease diagnosis and monitoring.

Potential Drug Target

ELOVL4 has been shown to play a role in the development and progression of various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. One potential mechanism by which ELOVL4 can be targeted as a drug is through its role in the regulation of cellular signaling pathways.

ELOVL4 is a key protein in the Src/FAK-associated signaling pathway, which is involved in the regulation of cell proliferation, migration, and survival. The Src/FAK-associated signaling pathway is a highly conserved protein that is involved in many cellular processes, including cell adhesion, cytoskeletal organization, and signaling pathways.

Studies have shown that ELOVL4 plays a critical role in the regulation of the Src/FAK-associated signaling pathway. ELOVL4 has been shown to interact with the protein FAK, which is a key component of the Src/FAK-associated signaling pathway. This interaction between ELOVL4 and FAK has been shown to play a role in the regulation of cellular signaling pathways, including the regulation of cell proliferation, migration, and survival.

In addition to its role in the Src/FAK-associated signaling pathway, ELOVL4 has also been shown to play a critical role in the regulation of cellular apoptosis. Apoptosis is a natural process that is involved in the regulation of cellular life and death, and it is often associated with the development and progression of diseases.

ELOVL4 has been shown to play a critical role in the regulation of apoptosis in various cellular contexts. For example, studies have shown that ELOVL4 can inhibit the caspase-3 dependent apoptosis in cancer cells, which may have implications for the development of new cancer therapies.

Potential Biomarker

ELOVL4 has also been shown to be a potential biomarker for various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. One potential mechanism by which ELOVL4 can be used as a biomarker is its ability to accumulate in the cells of individuals with certain diseases.

Studies have shown that ELOVL4 can accumulate in the cells of individuals with various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. This accumulation of ELOVL4 in cells has been shown to be associated with the development and progression of these diseases.

For example, studies have shown that ELOVL4 can accumulate in the cells of individuals with neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. This accumulation of ELOVL4 in cells has been shown to contribute to the development and progression of these disorders.

In addition to its potential as a biomarker, ELOVL4 has also been shown to be involved in the diagnosis and monitoring of various diseases. For example, studies have shown that ELOVL4 can be used as a biomarker for the diagnosis of cancer, as the accumulation of ELOVL4 in

Protein Name: ELOVL Fatty Acid Elongase 4

Functions: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of very long chain saturated (VLC-SFA) and polyunsaturated (PUFA) fatty acids that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development

The "ELOVL4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ELOVL4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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