Target Name: ELOF1
NCBI ID: G84337
Review Report on ELOF1 Target / Biomarker Content of Review Report on ELOF1 Target / Biomarker
ELOF1
Other Name(s): elongation factor 1 | ELOF1 variant 1 | ELOF1_HUMAN | ELF1 | elongation factor 1 homolog (ELF1, S. cerevisiae) | transcription elongation factor 1 homolog | Elongation factor 1, transcript variant 1 | ELF1 homolog, elongation factor 1 | Transcription elongation factor 1 homolog

ELOF1: A Potential Drug Target and Biomarker

ELOF1, or extendable long-chain 1, is a protein that is expressed in various tissues and cells throughout the body. Its primary function is to help regulate the length of DNA sequences in the chromosomes, which is essential for proper gene expression and development. ELOF1 has also been shown to play a role in the regulation of cellular processes such as cell division, apoptosis, and inflammation.

Recent studies have suggested that ELOF1 may have potential as a drug target or biomarker. In this article, we will explore the biology and potential therapeutic applications of ELOF1.

The biology of ELOF1

ELOF1 is a 21-kDa protein that is expressed in a variety of tissues, including muscle, heart, brain, and stem cells. It is primarily localized to the nuclei of these cells, where it is involved in the regulation of DNA replication and transcription.

One of the key functions of ELOF1 is its ability to extend the DNA double helix. This process is critical for the regulation of gene expression, as the length of the DNA sequence determines the level of gene expression. ELOF1 has been shown to play a role in the regulation of DNA replication, transcription, and apoptosis.

In addition to its role in regulating DNA, ELOF1 has also been shown to be involved in the regulation of cellular processes such as cell division, apoptosis, and inflammation. It has been shown to play a role in the regulation of the G1/S transition , which is a critical step in the cell cycle and is associated with the onset of cell division.

ELOF1 has also been shown to be involved in the regulation of apoptosis, which is a critical process for apoptosis, and inflammation, which is a critical process for immune response and tissue repair.

Potential therapeutic applications of ELOF1

The therapeutic potential applications of ELOF1 are vast and varied. As a drug target, ELOF1 has the potential to treat a variety of diseases and conditions, including cancer, neurodegenerative diseases, and inflammatory diseases.

One of the key potential therapeutic applications of ELOF1 is its ability to extend the DNA double helix, which may have therapeutic benefits in diseases that are characterized by DNA damage or dysfunction. For example, ELOF1 has been shown to play a role in the regulation of DNA replication and transcription in cancer cells, which suggests that it may have potential as a therapeutic target for cancer.

In addition to its potential as a cancer therapeutic, ELOF1 has also been shown to have potential in a variety of neurodegenerative diseases. For example, ELOF1 has been shown to play a role in the regulation of neurotransmitter release in neurons, which suggests that it may have potential as a therapeutic target for neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

ELOF1 has also been shown to have potential in treating inflammatory diseases. For example, ELOF1 has been shown to play a role in the regulation of inflammatory cytokine production in macrophages, which suggests that it may have potential as a therapeutic target for inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

In conclusion, ELOF1 is a protein that has been shown to play a critical role in a variety of biological processes and functions. Its potential as a drug target or biomarker makes it an attractive target for further research and development. Further studies are needed to fully Understand the biology and therapeutic applications of ELOF1, and to develop safe and effective therapies based on its unique properties.

Protein Name: Elongation Factor 1

Functions: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions

The "ELOF1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ELOF1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

Elongation Factor 1 Complex | Elongation of very long chain fatty acids protein | Elongin (SIII) complex | ELOVL1 | ELOVL2 | ELOVL2-AS1 | ELOVL3 | ELOVL4 | ELOVL5 | ELOVL6 | ELOVL7 | ELP1 | ELP2 | ELP3 | ELP4 | ELP5 | ELP6 | ELSPBP1 | EMB | EMBP1 | EMC1 | EMC1-AS1 | EMC10 | EMC2 | EMC3 | EMC3-AS1 | EMC4 | EMC6 | EMC7 | EMC8 | EMC9 | EMCN | EMD | EME1 | EME2 | EMG1 | EMID1 | EMILIN1 | EMILIN2 | EML1 | EML2 | EML2-AS1 | EML3 | EML4 | EML4-AS1 | EML5 | EML6 | EMP1 | EMP2 | EMP2P1 | EMP3 | EMSLR | EMSY | EMX1 | EMX2 | EMX2OS | EN1 | EN2 | ENAH | ENAM | ENC1 | ENDOD1 | ENDOG | Endogenous Retrovirus group K Env polyprotein (ERVK) | Endogenous retrovirus group K member 25 Pol protein-like, transcript variant X1 | EndoGlyx-1 | Endoplasmic reticulum collagen prolyl 3-hydroxylation complex | Endothelin receptor | Endothelin-Converting Enzymes (ECE) | Endothiapepsin | ENDOU | ENDOV | ENG | ENGASE | ENHO | ENKD1 | ENKUR | ENO1 | ENO1-AS1 | ENO1P1 | ENO1P4 | ENO2 | ENO3 | ENO4 | ENOPH1 | eNoSC Complex | ENOSF1 | ENOX1 | ENOX1-AS2 | ENOX2 | ENPEP | ENPP1 | ENPP2 | ENPP3 | ENPP4 | ENPP5 | ENPP6 | ENPP7 | ENPP7P10 | ENPP7P12