Target Name: SLITRK4
NCBI ID: G139065
Review Report on SLITRK4 Target / Biomarker Content of Review Report on SLITRK4 Target / Biomarker
SLITRK4
Other Name(s): SLIK4_HUMAN | SLITRK4 variant 2 | Slit and trk like gene 4 | DKFZp547M2010 | OTTHUMP00000024188 | OTTHUMP00000024187 | SLIT and NTRK like family member 4, transcript variant 2 | slit and trk like gene 4 | SLIT and NTRK-like protein 4 | SLIT and NTRK like family member 4

SLITRK4 Plays A Key Role in Cell-cell Adhesion and Cell Proliferation

SLITRK4 (SLIK4_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, muscle, and heart. It is a key regulator of cell-cell adhesion, which is the process by which cells stick together to form tissues and organs.

SLITRK4 is also involved in the regulation of cell proliferation, and has been shown to play a role in the development and progression of various diseases, including cancer.

Research has also suggested that SLITRK4 may be a potential drug target or biomarker, due to its involvement in multiple cellular processes that are relevant to a wide range of diseases.

SLITRK4 is a member of the SLT family of proteins, which are known for their role in cell-cell adhesion. This family of proteins includes several other proteins, including SLTN, SLTK1, and SLTK3, which are also involved in cell-cell adhesion.

SLITRK4 is a 21-kDa protein that is expressed in a variety of tissues and organs, including the brain, muscle, and heart. It is a key regulator of cell-cell adhesion, and has been shown to play a role in the development and progression of various diseases.

One of the key functions of SLITRK4 is its role in the regulation of cell proliferation.SLITRK4 has been shown to play a negative role in the regulation of cell proliferation, by inhibiting the activity of the oncogene transforming growth factor-beta (TGF-beta).

TGF-beta is a well-known transcription factor that is involved in the regulation of cellular processes that are relevant to the development and progression of many diseases, including cancer. By inhibiting the activity of TGF-beta, SLITRK4 may be able to prevent the uncontrolled growth and proliferation of cancer cells.

SLITRK4 is also involved in the regulation of the migration and invasion of cells.Migrating and invading cells are critical for the development and progression of many diseases, including cancer.SLITRK4 has been shown to play a role in the regulation of cell migration and invasion, by regulating the activity of the protein vimentin.

Vimentin is a microtubule protein that is involved in the regulation of cell movement and the formation of tissues. SLITRK4 has been shown to play a role in the regulation of vimentin activity, which may have implications for the development and progression of diseases.

In addition to its role in cell proliferation and migration, SLITRK4 is also involved in the regulation of cell-cell adhesion. This is the process by which cells stick together to form tissues and organs.SLITRK4 has been shown to play a key role in the regulation of cell-cell adhesion, by interacting with the protein E-cadherin.

E-cadherin is a transmembrane protein that is involved in cell-cell adhesion. It is a key regulator of cell-cell adhesion, and is involved in the development and progression of many diseases, including cancer.SLITRK4 has been shown to interact with E -cadherin, which may have implications for the regulation of cell-cell adhesion.

SLITRK4 is also involved in the regulation of the cytoskeleton. The cytoskeleton is the structure that gives cells shape and stability. SLITRK4 has been shown to play a role in the regulation of cytoskeleton structure and function, by interacting with the protein tubulin.

Protein Name: SLIT And NTRK Like Family Member 4

Functions: It is involved in synaptogenesis and promotes synapse differentiation (PubMed:27812321). Suppresses neurite outgrowth (By similarity)

The "SLITRK4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLITRK4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SLITRK5 | SLITRK6 | SLK | SLMAP | SLMO2-ATP5E | SLN | SLPI | SLTM | SLU7 | SLURP1 | SLURP2 | SLX1A | SLX1A-SULT1A3 | SLX1B | SLX1B-SULT1A4 | SLX4 | SLX4IP | SLX9 | SMAD | SMAD1 | SMAD1-AS1 | SMAD1-AS2 | SMAD2 | SMAD3 | SMAD4 | SMAD5 | SMAD5-AS1 | SMAD6 | SMAD7 | SMAD9 | SMAGP | Small Conductance Calcium-Activated Potassium Channel (SK) | SMAP1 | SMAP2 | SMARCA1 | SMARCA2 | SMARCA4 | SMARCA5 | SMARCAD1 | SMARCAD1-DT | SMARCAL1 | SMARCAL1-AS1 | SMARCB1 | SMARCC1 | SMARCC2 | SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 | SMC1A | SMC1B | SMC2 | SMC2-DT | SMC3 | SMC4 | SMC5 | SMC5-DT | SMC5-SMC6 Complex | SMC6 | SMCHD1 | SMCO1 | SMCO2 | SMCO3 | SMCO4 | SMCP | SMCR2 | SMCR5 | SMCR8 | SMDT1 | SMG1 | SMG1P1 | SMG1P2 | SMG1P3 | SMG1P4 | SMG1P5 | SMG5 | SMG6 | SMG7 | SMG7-AS1 | SMG8 | SMG9 | SMILR | SMIM1 | SMIM10 | SMIM10L1 | SMIM10L2A | SMIM10L2B | SMIM11 | SMIM12 | SMIM13 | SMIM14 | SMIM15 | SMIM17 | SMIM18 | SMIM19 | SMIM2 | SMIM2-AS1 | SMIM2-IT1 | SMIM20 | SMIM21