ABAT: A Drug Target / Disease Biomarker (G18)

Target Name: ABAT

NCBI ID: G18

ABAT

ABAT: A Drug Target / Disease Biomarker

ABAT, or adenosine binding protein, is a protein that is expressed in many different tissues throughout the body. It is primarily known for its role in the regulation of cell death and has been shown to play a potential role in a variety of diseases, including cancer.

One of the key functions of ABAT is its ability to bind to adenosine, a molecule that is naturally produced by the body and plays a critical role in many physiological processes. When adenosine binds to ABAT, it can stimulate the cell to undergo a process called apoptosis, which is the natural and controlled cell death that occurs when a cell is no longer needed or is damaged beyond repair.

ABAT has been shown to play a key role in the regulation of cell death in a variety of tissues and organs, including the brain, heart, and lungs. For example, studies have shown that ABAT levels are elevated in the brains of individuals with Alzheimer's disease, a progressive neurodegenerative disorder that is characterized by the accumulation of toxic proteins. Additionally, ABAT has been shown to be involved in the regulation of cell death in the lungs, where it has been shown to play a role in the development of fibrosis, a type of cancer that can cause chronic inflammation and the formation of scar tissue.

In addition to its role in cell death, ABAT has also been shown to play a potential role in the regulation of cell growth and proliferation. For example, studies have shown that ABAT can inhibit the growth and proliferation of cancer cells, a potential therapeutic approach for cancer treatment.

ABAT has also been shown to play a role in the regulation of inflammation and immune response. For example, studies have shown that ABAT is involved in the regulation of the production of immune cells, such as natural killer cells, which are critical for fighting off infections and diseases. Additionally, ABAT has been shown to play a role in the regulation of inflammation, which is a critical part of the immune response.

In conclusion, ABAT is a protein that has been shown to play a critical role in a variety of physiological processes throughout the body. Its ability to bind to adenosine and its role in the regulation of cell death, growth, and inflammation make it a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of ABAT in disease and to develop effective treatments.

Protein Name: 4-aminobutyrate Aminotransferase

Functions: Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively (PubMed:10407778, PubMed:15528998). Can also convert delta-aminovalerate and beta-alanine (By similarity)

The "ABAT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ABAT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets