ABCA13 (DKFZp313D2411) as a Drug Target and Biomarker: Implications for Cancer Treatment

Target Name: ABCA13

NCBI ID: G154664

ABCA13

ABCA13 (DKFZp313D2411) as a Drug Target and Biomarker: Implications for Cancer Treatment

Abstract:

ABCA13 (DKFZp313D2411) is a protein that is expressed in various tissues of the human body. Its function in cell biology is not well understood, but it has been associated with the development and progression of many diseases, including cancer. This protein has also been identified as a potential drug target and biomarker. In this article, we will discuss the potential implications of ABCA13 as a drug target and biomarker in cancer treatment.

Introduction:

Cancer is a leading cause of death worldwide, and its incidence is increasing every year. The development and progression of cancer is a complex process that involves the interplay of multiple factors, including genetic and epigenetic alterations, signaling pathways, and environmental factors. One of the factors that has been identified as a potential drug target in cancer treatment is ABCA13 (DKFZp313D2411).

ABCA13:

ABCA13 is a transmembrane protein that is expressed in various tissues of the human body, including the brain, heart, liver, and kidney. Its function in cell biology is not well understood, but it has been associated with the development and progression of many diseases, including cancer.

Potential Drug Target:

ABCA13 has been identified as a potential drug target in cancer treatment due to its unique structure and the various functions that have been associated with it. One of the key functions of ABCA13 is its role in the regulation of cell adhesion, which is a critical process that helps cells stick together and form tissues.

ABCA13 has also been shown to play a role in the regulation of angiogenesis, which is the process by which new blood vessels are formed to supply oxygen and nutrients to tissues. This is important for the growth and progression of cancer cells.

In addition, ABCA13 has also been shown to play a role in the regulation of cell signaling pathways, including the TGF-β pathway. This pathway is important for the development and maintenance of tissues, and it is a potential target for cancer treatments.

Biomarker:

ABCA13 has also been identified as a potential biomarker for cancer. The expression of ABCA13 has been shown to be elevated in various tissues of cancer, including the blood, lymph nodes, and tumors. This suggests that ABCA13 may be a useful biomarker for the diagnosis and evaluation of cancer.

In addition, studies have also shown that ABCA13 may be a potential target for cancer immunotherapy. Cancer immunotherapy involves the use of antibodies to target and destroy cancer cells. ABCA13 has been shown to be expressed in various tissues of cancer, including the blood, which suggests that it may be a useful target for cancer immunotherapy.

Conclusion:

In conclusion, ABCA13 is a protein that has been associated with the development and progression of many diseases, including cancer. Its function in cell biology is not well understood, but it has been shown to play a role in the regulation of cell adhesion, angiogenesis, and cell signaling pathways. As a potential drug target and biomarker, ABCA13 has the potential to revolutionize cancer treatment. Further research is needed to fully understand its functions and potential as a drug target and biomarker.

Protein Name: ATP Binding Cassette Subfamily A Member 13

Functions: May mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis dependent manner, thus playing a role in their internalization by endocytic retrograde transport and may also participate in the endocytosis of synaptic vesicle in cortical neurons

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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