Target Name: KCNV2
NCBI ID: G169522
Review Report on KCNV2 Target / Biomarker Content of Review Report on KCNV2 Target / Biomarker
KCNV2
Other Name(s): potassium voltage-gated channel modifier subfamily V member 2 | KV11.1 | Potassium voltage-gated channel subfamily V member 2 | RCD3B | Kv8.2 | Voltage-gated potassium channel subunit Kv8.2 | Potassium voltage-gated channel modifier subfamily V member 2 | potassium channel, voltage gated modifier subfamily V, member 2 | MGC120515 | potassium channel, subfamily V, member 2 | KCNV2_HUMAN | Voltage-gated potassium channel Kv8.2 | voltage-gated potassium channel subunit Kv8.2

KCNV2: A Drug Target / Disease Biomarker

KCNV2, also known as hsp70伪2, is a heat shock protein (HSP) that is expressed in various tissues and cells, including the heart, lungs, kidneys, and liver. It is a member of the HSP70 family, which is a group of proteins that are known to play a critical role in the regulation of protein synthesis and folding. HSPs are highly conserved, having similar structures and functions across different species.

KCNV2 is a 21-kDa protein that is expressed in the heart, lungs, and kidneys. It is involved in various physiological processes, including cell survival, growth, and inflammation. It has been shown to play a role in the regulation of ion homeostasis, cell signaling, and inflammation.

One of the unique features of KCNV2 is its ability to form a homotimeric complex with other HSPs, such as HSP70尾2 and HSP90. This creates a stable complex that is able to enhance the activity of these proteins. The homotimeric complex allows for the formation of a tight regulatory network, which is important for the regulation of protein function.

KCNV2 has also been shown to play a role in the regulation of cellular signaling pathways. It has been shown to interact with various signaling molecules, including TGF-β, NF-kappa-B, and p53. These interactions allow KCNV2 to regulate cellular processes such as cell growth, apoptosis, and inflammation.

In addition to its role in cellular signaling, KCNV2 has also been shown to play a critical role in the regulation of ion homeostasis. It is involved in the regulation of sodium and potassium homeostasis, which is important for maintaining the proper levels of these ions in the body. This is important for maintaining the proper functioning of various physiological processes, including muscle and nerve function.

KCNV2 has also been shown to play a role in the regulation of inflammation. It has been shown to interact with various signaling molecules, including TNF-伪, IL-1, and IL-6. These interactions allow KCNV2 to contribute to the regulation of inflammatory responses.

Despite its importance in various physiological processes, KCNV2 is not yet a drug target or biomarker. There is ongoing research into the potential benefits and risks of targeting this protein, including the development of potential therapeutic compounds.

In conclusion, KCNV2 is a highly conserved and versatile protein that plays a critical role in various physiological processes. Its ability to form a homotimeric complex with other HSPs and its involvement in the regulation of cellular signaling pathways, ion homeostasis, and inflammation make it an attractive target for future research. Further studies are needed to determine the full extent of its functions and the potential benefits and risks of targeting this protein.

Protein Name: Potassium Voltage-gated Channel Modifier Subfamily V Member 2

Functions: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values

The "KCNV2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KCNV2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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KCP | KCTD1 | KCTD10 | KCTD11 | KCTD12 | KCTD13 | KCTD13-DT | KCTD14 | KCTD15 | KCTD16 | KCTD17 | KCTD18 | KCTD19 | KCTD2 | KCTD20 | KCTD21 | KCTD21-AS1 | KCTD3 | KCTD4 | KCTD5 | KCTD5P1 | KCTD6 | KCTD7 | KCTD8 | KCTD9 | KDELR1 | KDELR2 | KDELR3 | KDF1 | KDM1A | KDM1B | KDM2A | KDM2B | KDM3A | KDM3B | KDM4A | KDM4B | KDM4C | KDM4D | KDM4E | KDM5A | KDM5A-GATAD1-EMSY chromatin complex | KDM5B | KDM5C | KDM5D | KDM6A | KDM6B | KDM7A | KDM7A-DT | KDM8 | KDR | KDSR | KEAP1 | Kelch-like protein | KERA | Keratin | KHDC1 | KHDC1L | KHDC1P1 | KHDC3L | KHDC4 | KHDRBS1 | KHDRBS2 | KHDRBS3 | KHK | KHNYN | KHSRP | KHSRPP1 | KIAA0040 | KIAA0087 | KIAA0232 | KIAA0319 | KIAA0319L | KIAA0408 | KIAA0513 | KIAA0586 | KIAA0753 | KIAA0754 | KIAA0825 | KIAA0930 | KIAA1107 | KIAA1143 | KIAA1191 | KIAA1210 | KIAA1217 | KIAA1328 | KIAA1522 | KIAA1549 | KIAA1549L | KIAA1586 | KIAA1614 | KIAA1656 | KIAA1671 | KIAA1671-AS1 | KIAA1755 | KIAA1958 | KIAA2012 | KIAA2013 | KIAA2026 | KICS2