Unlocking The Potential of KCTD11: A Protein with Potential as A Drug Target Or Biomarker

Target Name: KCTD11

NCBI ID: G147040

KCTD11

Unlocking The Potential of KCTD11: A Protein with Potential as A Drug Target Or Biomarker

KCTD11 is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and pancreas. It is a member of the kallikrein gene family, which includes several similar proteins that play important roles in various physiological processes. One of the most interesting aspects of KCTD11 is its potential as a drug target or biomarker.

The kallikrein gene family is known for producing a variety of structurally similar proteins that share a common catalytic domain. These proteins are involved in a wide range of physiological processes, including blood clotting, tissue repair, and inflammation. KCTD11 is no exception to this rule, as it is a member of the kallikrein gene family that is known to produce the protein kallikrein-related peptidases (KLK1s).

KLK1s are a group of proteins that are involved in the degradation of extracellular matrix (ECM) components, such as collagen and hyaluronic acid. These proteins are thought to play an important role in the regulation of tissue repair and regeneration, as well as in the inflammatory response. One of the most interesting aspects of KLK1s is their potential as drug targets or biomarkers.

KCTD11 is a 14-kDa protein that is expressed in various tissues of the body, including the brain, heart, liver, and pancreas. It is a member of the kallikrein gene family and is involved in the production of KLK1s. KCTD11 has been shown to play an important role in the regulation of inflammation and tissue repair.

One of the most interesting aspects of KCTD11 is its potential as a drug target. KLK1s have been shown to play an important role in the regulation of inflammation and tissue repair, making them an attractive target for drug development. Additionally, KLK1s are known to be involved in the regulation of cell adhesion and migration, which may have implications for the development of new therapies for a variety of diseases.

In addition to its potential as a drug target, KCTD11 may also be a useful biomarker for the diagnosis and monitoring of various diseases. For example, KCTD11 has been shown to be involved in the regulation of inflammation and tissue repair in a variety of diseases, including cancer, autoimmune diseases, and neurodegenerative diseases. Additionally, KCTD11 may be a useful biomarker for monitoring the effectiveness of certain therapies, as its levels can be affected by the treatment.

Overall, KCTD11 is a protein that has the potential to be a drug target or biomarker. Its involvement in the regulation of inflammation and tissue repair makes it an attractive target for drug development, and its involvement in the regulation of cell adhesion and migration may have implications for the development of new therapies for a variety of diseases. Further research is needed to fully understand the role of KCTD11 in these processes and to develop new treatments based on its properties.

Protein Name: Potassium Channel Tetramerization Domain Containing 11

Functions: Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Acts as probable substrate-specific adapter for a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex towards HDAC1. Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcription factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state, this effect probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. When knock-down, Hedgehog antagonism is impaired and proliferation of granule cells is sustained. Activates the caspase cascade

The "KCTD11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KCTD11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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