KDM3B's Role in Cancer: Regulating DNA Replication and Cell Cycle

Target Name: KDM3B

NCBI ID: G51780

KDM3B

KDM3B's Role in Cancer: Regulating DNA Replication and Cell Cycle

KDM3B (KDM3B) is a protein that is located in the nuclei of human cells. It plays a crucial role in the regulation of DNA replication and has been linked to a number of diseases, including cancer.

In cancer, KDM3B is often overexpressed, which means that it is produced in greater quantities than normal. This can lead to the formation of tumors and the development of cancer.

One of the ways that KDM3B has been linked to cancer is through its role in the regulation of the DNA replication process. In cancer cells, the DNA replication process is often poorly controlled, which allows the cells to multiply rapidly and to uncontrolled grow.

KDM3B has been shown to play a role in regulating the DNA replication process in cancer cells. It has been shown to interact with the protein p53, which is a well-known regulator of the DNA replication process.

KDM3B has also been shown to be involved in the regulation of cell cycle progression. In cancer cells, the cell cycle is often disrupted, which allows the cells to multiply rapidly and to develop a more aggressive form of cancer.

KDM3B has been shown to play a role in the regulation of the cell cycle by affecting the levels of the protein cyclin D1. Cyclin D1 is a protein that helps to control the length of the cell cycle by regulating the movement of the chromosomes along the DNA.

In addition to its role in the regulation of the DNA replication process and the cell cycle, KDM3B has also been shown to be involved in the regulation of gene expression. In cancer cells, the levels of many proteins are often disrupted, which allows the cells to develop a more aggressive form of cancer.

KDM3B has been shown to play a role in the regulation of gene expression by affecting the levels of the protein Ku70. Ku70 is a protein that is involved in the regulation of DNA replication and has been shown to play a role in the development of cancer.

In conclusion, KDM3B is a protein that has been linked to a number of diseases, including cancer. It plays a crucial role in the regulation of DNA replication and has been shown to interact with the protein p53 and the protein cyclin D1. It may also play a role in the regulation of gene expression and the cell cycle. Further research is needed to fully understand the role of KDM3B in these processes and to develop effective treatments for cancer.

Protein Name: Lysine Demethylase 3B

Functions: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity

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