KDM2A: A Key Protein in Cellular Processes (G22992)

Target Name: KDM2A

NCBI ID: G22992

KDM2A

KDM2A: A Key Protein in Cellular Processes

The F-box and leucine-rich repeat protein 11 (KDM2A) is a protein that plays a crucial role in various cellular processes. It is a key player in the histone regulation, which is a process that involves the modification of the histones, which are small proteins that make up the nuclei of cells. Histones play a vital role in organizing DNA in the nucleus and influencing gene expression.

KDM2A is a protein that contains a unique F-box and a leucine-rich repeat. The F-box is a structural protein that plays a vital role in the regulation of various cellular processes. It is a common protein found in various cell types and is involved in the regulation of cell growth, differentiation, and apoptosis. The leucine-rich repeat is a structural protein that is found in various proteins and is involved in the regulation of protein function.

KDM2A is a protein that has been shown to play a crucial role in the regulation of histone modification. Histone modification is a process that involves the addition of various chemical groups to the histones, which can alter their stability and influence gene expression. KDM2A is involved in the regulation of the addition of the histone acetyl group, which is one of the most well-known histone modifications.

KDM2A has also been shown to play a role in the regulation of cell growth and apoptosis. It is involved in the regulation of cell cycle progression, which is the process by which cells divide and grow. KDM2A has been shown to play a role in the regulation of the G1 phase of the cell cycle, which is the stage of cell growth and preparation for cell division.

In addition to its role in cell growth and apoptosis, KDM2A has also been shown to play a role in the regulation of inflammation. It is involved in the regulation of the immune response, which is the process by which the body defends itself against external threats such as viruses and bacteria.

KDM2A is also a protein that has been shown to play a role in the regulation of protein stability. It is involved in the regulation of protein stability by affecting the addition of various chemical groups to the protein.

KDM2A is a protein that has been shown to play a crucial role in various cellular processes. Its unique F-box and leucine-rich repeat structure make it a potential drug target and biomarker for various diseases. Further research is needed to fully understand the role of KDM2A in cellular processes and its potential as a drug target.

Protein Name: Lysine Demethylase 2A

Functions: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-BMAL1 heterodimer and RORA in a catalytically-independent manner (PubMed:26037310)

The "KDM2A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KDM2A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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