Target Name: KDELR3
NCBI ID: G11015
Review Report on KDELR3 Target / Biomarker Content of Review Report on KDELR3 Target / Biomarker
KDELR3
Other Name(s): ERD23 | KDEL endoplasmic reticulum protein retention receptor 3, transcript variant 2 | ER lumen protein-retaining receptor 3 | KDELR3 variant 2 | ERD23_HUMAN | KDEL receptor 3 | ERD2L3 | ER lumen protein-retaining receptor 3 (isoform b) | OTTHUMP00000028924 | KDEL endoplasmic reticulum protein retention receptor 3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | ER lumen protein retaining receptor 3

KDELR3: A Potential Drug Target for Kinesin System and Beyond

KDELR3 (Kinesin-associated protein with light chain 3) is a protein that is expressed in various tissues and cells throughout the body. It is a key component of the kinesin system, which is a protein structure that plays a crucial role in the movement of cells and organelles within cells. KDELR3 is a 21-kDa protein that is expressed in the brain, heart, and skeletal muscles.

One of the unique features of KDELR3 is its light chain, which is a portion of the protein that is responsible for the protein's ability to interact with the kinesin system. The light chain is composed of two subunits, which are held together by a disulfide bond . This subunit contains a unique domain that is known as the N-terminus alpha-helix, which is a region of the protein that is involved in the formation of the protein's alpha-helices.

KDELR3 is a protein that has been identified as a potential drug target due to its involvement in the kinesin system. The kinesin system is a complex protein structure that is involved in the movement of cells and organelles within cells. It is composed of a series of proteins, including KDELR3, that work together to regulate the movement of these structures.

KDELR3 is a key component of the kinesin system because it is involved in the formation of the protein's alpha-helices. The alpha-helices are the helix-like structures that are formed by the arrangement of the amino acids that make up the protein's monomers. These helices play a crucial role in the stability and function of the protein, and they are also involved in the protein's ability to interact with the kinesin system.

Research has shown that KDELR3 is involved in the regulation of the kinesin system in a number of different ways. For example, studies have shown that KDELR3 is involved in the regulation of the speed at which the kinesin system moves, as well as the direction of movement. Additionally, KDELR3 has been shown to play a role in the regulation of the stability of the kinesin system, as well as the interaction between the kinesin system and other proteins.

In addition to its involvement in the kinesin system, KDELR3 has also been shown to have a number of potential drug targets. For example, studies have shown that KDELR3 is involved in the regulation of cell division, and that it is involved in the development and progression of a number of different diseases, including cancer. Additionally, KDELR3 has been shown to play a role in the regulation of the immune system, and that it is involved in the regulation of inflammation.

Overall, KDELR3 is a protein that is involved in a number of different processes in the body. Its involvement in the kinesin system, as well as its potential drug target status, makes it an interesting target for research and development of new therapies.

Protein Name: KDEL Endoplasmic Reticulum Protein Retention Receptor 3

Functions: Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum

The "KDELR3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KDELR3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KDF1 | KDM1A | KDM1B | KDM2A | KDM2B | KDM3A | KDM3B | KDM4A | KDM4B | KDM4C | KDM4D | KDM4E | KDM5A | KDM5A-GATAD1-EMSY chromatin complex | KDM5B | KDM5C | KDM5D | KDM6A | KDM6B | KDM7A | KDM7A-DT | KDM8 | KDR | KDSR | KEAP1 | Kelch-like protein | KERA | Keratin | KHDC1 | KHDC1L | KHDC1P1 | KHDC3L | KHDC4 | KHDRBS1 | KHDRBS2 | KHDRBS3 | KHK | KHNYN | KHSRP | KHSRPP1 | KIAA0040 | KIAA0087 | KIAA0232 | KIAA0319 | KIAA0319L | KIAA0408 | KIAA0513 | KIAA0586 | KIAA0753 | KIAA0754 | KIAA0825 | KIAA0930 | KIAA1107 | KIAA1143 | KIAA1191 | KIAA1210 | KIAA1217 | KIAA1328 | KIAA1522 | KIAA1549 | KIAA1549L | KIAA1586 | KIAA1614 | KIAA1656 | KIAA1671 | KIAA1671-AS1 | KIAA1755 | KIAA1958 | KIAA2012 | KIAA2013 | KIAA2026 | KICS2 | KIDINS220 | KIF11 | KIF12 | KIF13A | KIF13B | KIF14 | KIF15 | KIF16B | KIF17 | KIF18A | KIF18B | KIF19 | KIF1A | KIF1B | KIF1C | KIF20A | KIF20B | KIF21A | KIF21B | KIF22 | KIF23 | KIF23-AS1 | KIF24 | KIF25 | KIF25-AS1 | KIF26A | KIF26B | KIF27