Target Name: KIAA1328
NCBI ID: G57536
Review Report on KIAA1328 Target / Biomarker Content of Review Report on KIAA1328 Target / Biomarker
KIAA1328
Other Name(s): K1328_HUMAN | hinderin | Hinderin | Protein hinderin | KIAA1328 variant 1 | KIAA1328, transcript variant 1 | Protein hinderin (isoform 1)

KIAA1328: A Potential Drug Target Or Biomarker

KIAA1328 (K1328_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a part of the Kallikrein-related peptidases (KAPs) family, which are a group of enzymes that generate calcification end products during the calcification process.

KIAA1328 has been identified as a potential drug target or biomarker for various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. Its role in these diseases is not well understood, but its potential as a drug target is based on its known functions in the calcification process and its expression in different tissues.

One of the functions of KIAA1328 is its role in the calcification process. This protein is involved in the production of micro-calcification, which is the accumulation of calcium salts in the extracellular matrix of cells. Micro-calcification is a common occurrence in various tissues and is associated with the development of various diseases, including cancer, neurodegenerative disorders, and cardiovascular disease.

KIAA1328 is also involved in the regulation of the calcification process. It has been shown to play a role in the regulation of extracellular matrix (ECM) mineral content, which is critical for the maintenance of tissue architecture and function. The ECM is a complex matrix of proteins, minerals, and other substances that are present in the body and plays a vital role in supporting the growth, repair, and adaptation of tissues.

In addition to its role in the calcification process, KIAA1328 has also been shown to be involved in the regulation of cellular signaling. It is a known substrate for several enzymes involved in intracellular signaling, including the protein kinase A (PKA) and the protein tyrosine phosphatase (PTP). These enzymes are involved in the regulation of various cellular processes, including cell growth, differentiation, and survival.

The potential drug target status of KIAA1328 is based on its expression in different tissues and its involvement in the calcification process and cellular signaling. However, more research is needed to fully understand its functions and potential as a drug target.

In conclusion, KIAA1328 is a protein that is expressed in various tissues of the human body and is involved in the calcification process. Its potential as a drug target or biomarker for various diseases is based on its known functions in the calcification process and its expression in different tissues. Further research is needed to fully understand its functions and potential as a drug target.

Protein Name: KIAA1328

Functions: Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes

The "KIAA1328 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIAA1328 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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