FBXO21: Potential Drug Target Or Biomarker for Various Diseases

Target Name: FBXO21

NCBI ID: G23014

FBXO21

FBXO21: Potential Drug Target Or Biomarker for Various Diseases

The F-box protein 21 (FBXO21) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and muscle. It is a member of the F-box gene family, which is known for the presence of a conserved structural motif called the F-box in the protein sequence. FBXO21 is a transcript variant of the gene that has been shown to play a role in various cellular processes, including cell signaling, DNA replication, and protein stability.

One of the unique features of FBXO21 is its ability to interact with other proteins, particularly with the protein called p53. P53 is a well-known tumor suppressor protein that is often mutated in cancer and can lead to the development of various diseases, including cancer . FBXO21 has been shown to physically interact with p53 and can modulate its activity. This interaction between FBXO21 and p53 suggests that it may be a potential drug target or biomarker for various diseases.

In addition to its interaction with p53, FBXO21 has also been shown to play a role in the regulation of DNA replication. During DNA replication, the protein is involved in the formation of a double helix and has been shown to play a role in the regulation of the initiation complex formation and stability. Furthermore, FBXO21 has also been shown to be involved in the regulation of protein stability, which is important for the proper function of many proteins and is a key factor in various cellular processes.

Another potential drug target for FBXO21 is its role in cell signaling. FBXO21 has been shown to be involved in various signaling pathways, including the TGF-β pathway. This suggests that it may play a role in the regulation of cellular processes that are important for the development and maintenance of tissues and organs, including organs and tissues.

FBXO21 has also been shown to have a role in the regulation of cellular processes related to the immune response. During the immune response, FBXO21 is involved in the regulation of the movement of immune cells to the site of infection or inflammation. This suggests that it may play a role in the regulation of the immune response and contribute to the development of autoimmune diseases.

In conclusion, FBXO21 is a protein that has been shown to play a role in various cellular processes, including cell signaling, DNA replication, and protein stability. Its ability to interact with the protein called p53 and the regulation of DNA replication, protein stability, and the immune response suggest that it may be a potential drug target or biomarker for various diseases. Further research is needed to fully understand the role of FBXO21 in these cellular processes and its potential as a drug target or biomarker.

Protein Name: F-box Protein 21

Functions: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex

The "FBXO21 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FBXO21 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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