Understanding OR4C15: A Potential Drug Target and Biomarker (G81309)
Understanding OR4C15: A Potential Drug Target and Biomarker
Olfactory receptor 4C15 (OR4C15) is a protein that is expressed in the olfactory system, which is responsible for the sense of smell. OR4C15 is a G protein-coupled receptor (GPCR), which is a type of transmembrane protein that plays an important role in sensory perception. GPCRs are a family of membrane proteins that are involved in a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and cell signaling.
OR4C15 is a member of the subfamily of GPCRs known as GPCR-C8, which is characterized by the presence of a nucleotide-binding oligomerization (NBO) domain and a carboxy-terminal hypervariable region (HVR). The NBO domain is a conserved protein region that is involved in the formation of a protein-protein interaction network, while the HVR is a variable region that is involved in the recognition of extracellular signals.
OR4C15 is expressed in the olfactory system, which is responsible for the sense of smell. The olfactory system consists of the olfactory neurons, which are located in the nasal cavity, and the olfactory cortex, which is the part of the brain that is responsible for processing and interpreting the sense of smell. OR4C15 is expressed in the olfactory neurons and is involved in the development and function of these neurons.
OR4C15 is a potential drug target (or biomarker) because of its involvement in sensory perception and neurotransmission. GPCRs are involved in the transmission of sensory information from the sensory system to the brain, and are potential targets for drugs that can modulate sensory perception. OR4C15 is also involved in the neurotransmission of olfactory information, which may make it a useful target for drugs that can modulate neurotransmission.
One way to study the potential drug targets for OR4C15 is to use techniques such as pharmacological screening experiments. These experiments involve administering small molecules to cells or animals and observing the effects on the behavior or physiology of the cells or animals. By using pharmacological screening experiments , researchers can identify potential drug candidates that can modulate the activity of OR4C15.
Another way to study the potential drug targets for OR4C15 is to use gene editing techniques. These techniques involve modifying the DNA of cells or animals to introduce mutations that can affect the activity of the gene. By using gene editing techniques, researchers can identify potential drug targets that are mutated or otherwise modified in a way that affects the activity of OR4C15.
OR4C15 is also a potential biomarker for the diagnosis and monitoring of various neurological and psychiatric disorders. For example, altered activity of OR4C15 has been observed in the brains of patients with Alzheimer's disease, a progressive neurodegenerative disorder that is characterized by the accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain. This suggests that OR4C15 may be a useful biomarker for the diagnosis and monitoring of Alzheimer's disease.
In conclusion, OR4C15 is a protein that is expressed in the olfactory system and is involved in the sense of smell. OR4C15 is a member of the GPCR-C8 subfamily and is characterized by the presence of an NBO domain and an HVR. OR4C15 is expressed in the olfactory neurons and is involved in the development and function of these neurons. It is also a potential drug target (or biomarker) for the diagnosis and treatment of various neurological and psychiatric disorders. Further research is needed to fully understand the role of OR4C15 in sensory perception and neurotransmission.
Protein Name: Olfactory Receptor Family 4 Subfamily C Member 15
Functions: Odorant receptor
The "OR4C15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR4C15 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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