OR2Z1: A Potential Drug Target for Neurodegenerative and Cancer-Related Diseases
OR2Z1: A Potential Drug Target for Neurodegenerative and Cancer-Related Diseases
OR2Z1 (OR19-4) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, and gastrointestinal tract. It is a member of the superfamily of G-coupled proteins, which are a type of transmembrane protein that consists of a catalytic active site, a transmembrane region, and an intracellular region.
OR2Z1 is involved in a variety of physiological processes in the body, including cell signaling, neurotransmitter signaling, and immune responses. Its function is thought to be related to the regulation of cell adhesion, migration, and survival.
Due to its involvement in so many important cellular processes, OR2Z1 has been identified as a potential drug target. Researchers are currently investigating the potential benefits and risks of targeting OR2Z1, with the goal of developing new treatments for a variety of diseases.
One of the main reasons for the interest in OR2Z1 is its involvement in neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. These conditions are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles, which can lead to a range of symptoms such as memory loss, stiffness, and difficulty with movement.
Previous studies have shown that OR2Z1 is expressed in the brains of individuals with Alzheimer's disease and that its levels are decreased in the brains of individuals with Parkinson's disease. Additionally, studies have shown that targeting OR2Z1 with small molecules has the potential to protect against neurodegeneration in these conditions.
Another promising aspect of OR2Z1 is its involvement in cancer. Many studies have shown that OR2Z1 is expressed in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, studies have shown that targeting OR2Z1 with small molecules has the potential to inhibit cancer cell growth and metastasis.
OR2Z1 is also involved in the regulation of cell signaling pathways that are important for many cellular processes, including cell adhesion, migration, and survival. Its role in these processes is thought to be related to its ability to interact with various signaling molecules, including TGF-β1, PDGF, and NF-kappa-B.
Additionally, OR2Z1 is involved in the regulation of the immune response. Studies have shown that OR2Z1 is expressed in immune cells and that it plays a role in the regulation of immune cell function. Its role in this process is thought to be related to its ability to interact with various signaling molecules, including PD-L1 and NF-kappa-B.
Overall, OR2Z1 is a protein that is involved in a variety of important cellular processes and its function is thought to be related to the regulation of cell adhesion, migration, and survival. Its potential as a drug target makes it an attractive target for the development of new treatments for a variety of diseases.
Protein Name: Olfactory Receptor Family 2 Subfamily Z Member 1
Functions: Odorant receptor
The "OR2Z1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR2Z1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
OR3A1 | OR3A2 | OR3A3 | OR3A4P | OR4A14P | OR4A15 | OR4A16 | OR4A17P | OR4A21P | OR4A47 | OR4A5 | OR4B1 | OR4C11 | OR4C12 | OR4C13 | OR4C15 | OR4C16 | OR4C1P | OR4C3 | OR4C45 | OR4C46 | OR4C5 | OR4C50P | OR4C6 | OR4D1 | OR4D10 | OR4D11 | OR4D2 | OR4D5 | OR4D6 | OR4D9 | OR4E2 | OR4F13P | OR4F15 | OR4F16 | OR4F17 | OR4F21 | OR4F29 | OR4F3 | OR4F4 | OR4F5 | OR4F6 | OR4G3P | OR4K1 | OR4K13 | OR4K14 | OR4K15 | OR4K17 | OR4K2 | OR4K5 | OR4K6P | OR4K7P | OR4L1 | OR4M1 | OR4M2 | OR4M2-OT1 | OR4N2 | OR4N3P | OR4N4 | OR4N5 | OR4P4 | OR4Q3 | OR4S1 | OR4S2 | OR4T1P | OR4V1P | OR4X1 | OR4X2 | OR51A1P | OR51A2 | OR51A3P | OR51A4 | OR51A6P | OR51A7 | OR51B2 | OR51B4 | OR51B5 | OR51B6 | OR51C1P | OR51D1 | OR51E1 | OR51E2 | OR51F1 | OR51F2 | OR51G1 | OR51G2 | OR51H1 | OR51I1 | OR51I2 | OR51J1 | OR51L1 | OR51M1 | OR51Q1 | OR51S1 | OR51T1 | OR51V1 | OR52A1 | OR52A4P | OR52A5 | OR52B2
