Target Name: PHLDA1
NCBI ID: G22822
Review Report on PHLDA1 Target / Biomarker Content of Review Report on PHLDA1 Target / Biomarker
PHLDA1
Other Name(s): Pleckstrin homology like domain family A member 1 | T cell death associated gene 51 | PHRIP | Pleckstrin homology-like domain family A member 1 | MGC131738 | apoptosis-associated nuclear protein | T-cell death-associated gene 51 protein | proline-histidine rich protein | PHLA1_HUMAN | pleckstrin homology like domain family A member 1 | DT1P1B11 | PQ-rich protein | Proline- and glutamine-rich protein | Apoptosis-associated nuclear protein | PQR protein | proline- and histidine-rich protein | Proline- and histidine-rich protein | proline- and glutamine-rich protein | TDAG51

PHLDA1: Key Regulator of Cell Signaling and Adhesion

PHLDA1 (Pleckstrin homology like domain family A member 1) is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. It is a member of the PHLDA family, which is characterized by the presence of a specific domain that is similar to the protein family 1 of the superfamily P1/P12/P13.

The PHLDA1 protein is involved in various cellular processes in the body, including cell signaling, cell adhesion, and cell survival. It is a key regulator of the Shc/FAK signaling pathway, which is a well-established pathway that regulates many cellular processes in the body, including cell growth, differentiation, and survival.

PHLDA1 is also known as CSN2 (clusterin-like protein N2), and it is a member of the CSN family, which is characterized by the presence of a specific domain in the protein that is similar to the protein family 1 of the superfamily P1/ P12/P13. The CSN family is a family of proteins that are involved in various cellular processes, including cell signaling, cell adhesion, and cell survival.

PHLDA1 is a 200-kDa protein that is expressed in various tissues of the human body, including the brain, heart, and liver. It is characterized by the presence of a specific domain that is similar to the protein family 1 of the superfamily P1/ P12/P13. The PHLDA1 protein is involved in various cellular processes in the body, including cell signaling, cell adhesion, and cell survival.

One of the key functions of PHLDA1 is its role in the Shc/FAK signaling pathway. This pathway is a well-established pathway that regulates many cellular processes in the body, including cell growth, differentiation, and survival. The Shc protein is a key regulator of this pathway, and it is involved in the regulation of various cellular processes in the body.

PHLDA1 is also involved in the regulation of cell adhesion and cell survival. It is a key regulator of the adherens protein, which is involved in cell adhesion. In addition, PHLDA1 is involved in the regulation of cell survival, as it is a key regulator of the p53 protein, which is involved in the regulation of DNA damage repair.

PHLDA1 is also involved in the regulation of cellular signaling pathways. It is a key regulator of the FAK/PAK signaling pathway, which is involved in the regulation of cell signaling and cell adhesion. In addition, PHLDA1 is involved in the regulation of the Src /FAK signaling pathway, which is involved in the regulation of cell signaling and cell adhesion.

PHLDA1 is also involved in the regulation of cellular structure and dynamics. It is a key regulator of the cytoskeleton, as it is involved in the regulation of actin filament organization and dynamics. In addition, PHLDA1 is involved in the regulation of the cell membrane, as it is involved in the regulation of the cytoskeleton and the cell membrane.

PHLDA1 is also involved in the regulation of cellular transport. It is a key regulator of the Na+/K+-ATPase, which is involved in the regulation of cell transport. In addition, PHLDA1 is involved in the regulation of the Mg2+/ATPase, which is involved in the regulation of cell transport.

In conclusion, PHLDA1 is a protein that is involved in various cellular processes in the human body. It is a key regulator of the Shc/FAK signaling pathway, and it is involved in the regulation of cell signaling, cell adhesion, and cell survival. As a result, PHLDA1 is a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

Protein Name: Pleckstrin Homology Like Domain Family A Member 1

Functions: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation

The "PHLDA1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PHLDA1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1 | PICSAR | PID1 | PIDD1 | PIERCE1 | PIERCE2 | PIEZO1 | PIEZO2 | PIF1 | PIFO | PIGA | PIGB | PIGBOS1 | PIGC | PIGF | PIGG | PIGH | PIGK | PIGL | PIGM | PIGN | PIGO | PIGP | PIGQ | PIGR | PIGS | PIGT | PIGU | PIGV | PIGW | PIGX | PIGY | PIGZ | PIH1D1 | PIH1D2 | PIK3AP1 | PIK3C2A | PIK3C2B | PIK3C2G | PIK3C3 | PIK3CA