PIGV: Development and Maintenance of Tissues and Organs (G55650)

Target Name: PIGV

NCBI ID: G55650

PIGV

PIGV: Development and Maintenance of Tissues and Organs

Phosphatidylinositol glycan anchor biosynthesis class V (PIGV) is a protein that plays a crucial role in the development and maintenance of various tissues and organs in higher vertebrates, including humans. PIGV is a member of the PIG family, which includes several other proteins involved in the biosynthesis of intracellular signaling molecules, such as PIG1, PIG2, and PIG3.

PIGV is expressed in a variety of tissues and organs, including brain, heart, skeletal muscles, and organs. It is involved in the production of various signaling molecules, including insulin, growth factors, and cytokines. PIGV has been shown to play a role in the regulation of cellular processes such as cell adhesion, migration, and survival.

PIGV is also involved in the production of cell surface antigens, which are proteins that are expressed on the surface of cells and can interact with other cells and molecules. These antigens are important for the development and maintenance of tissues and organs, and are often used as potential drug targets or biomarkers.

One of the unique features of PIGV is its ability to produce multiple isoforms of the protein, which are different in their size and function. These isoforms are produced through alternative splicing, a process by which the DNA sequence of the gene is transcribed into a RNA molecule, and then translated into a protein.

PIGV has been shown to play a role in the development and maintenance of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. For example, studies have shown that PIGV is involved in the development of neurofibrillary tangles, which are a hallmark of Alzheimer's disease, and that it plays a role in the regulation of pain signaling.

In addition to its role in the development and maintenance of tissues and organs, PIGV is also involved in the regulation of cellular processes that are important for the survival and function of cells. For example, PIGV has been shown to play a role in the regulation of cell death, as well as the control of cell cycle progression.

Given its involvement in a variety of cellular processes, PIGV is an attractive drug target or biomarker for a variety of diseases. For example, PIGV has been shown to be a potential therapeutic target for neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

In addition to its potential therapeutic applications, PIGV is also a valuable tool for the study of cellular biology and development. The isoforms of PIGV can be used as a tool for studying the regulation of alternative splicing and the production of diverse proteins from a single gene.

Overall, PIGV is a complex protein that plays a crucial role in the development and maintenance of various tissues and organs. Its involvement in the production of cell surface antigens and its ability to produce multiple isoforms make it an attractive drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of PIGV in cellular biology and its potential as a therapeutic target.

Protein Name: Phosphatidylinositol Glycan Anchor Biosynthesis Class V

Functions: Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly

The "PIGV Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PIGV comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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