Uncovering The Unique Functions of KIF13A: A Protein of Great Interest To Researchers

Target Name: KIF13A

NCBI ID: G63971

KIF13A

Uncovering The Unique Functions of KIF13A: A Protein of Great Interest To Researchers

Kinesin family member 13A (KIF13A) is a protein that is expressed in various tissues throughout the body, including muscle, brain, and heart. It is a member of the Kinesin family, which is a well-known family of proteins that are involved in the transport of vesicles and organelles throughout the cell.

KIF13A is unique among its family members because of its unique structure and function. Unlike other Kinesin proteins, KIF13A has a C-terminal hypervariable region (HVR), which is a region of the protein that is highly variable and can differ among different species. This HVR allows KIF13A to have a wide range of functions, including acting as a drug target and serving as a biomarker for certain diseases.

One of the most interesting functions of KIF13A is its role as a drug target. KIF13A has been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders. Researchers have identified several potential drug targets for KIF13A, including those that target its HVR and its function as a regulator of the actin cytoskeleton.

In addition to its potential as a drug target, KIF13A has also been shown to serve as a biomarker for certain diseases. Its expression has been detected in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This suggests that KIF13A may be a useful biomarker for these diseases and could potentially be used in diagnostic tests.

KIF13A is also of interest to researchers because of its unique structure and function. Its HVR allows it to have a wide range of functions, including acting as a regulator of the actin cytoskeleton, transports organelles, and plays a role in the regulation of cell division.

Overall, KIF13A is a protein that is of great interest to researchers due to its unique structure and function. Its potential as a drug target and biomarker make it an attractive target for further study, and its unique structure may hold clues to its functions in the cell.

Protein Name: Kinesin Family Member 13A

Functions: Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis

The "KIF13A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIF13A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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