KIDINS220: A Potential Drug Target Or Biomarker (G57498)

Target Name: KIDINS220

NCBI ID: G57498

KIDINS220

KIDINS220: A Potential Drug Target Or Biomarker

KIDINS220 (ARMS) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Insulin-like growth factor (IGF) family, which is a group of transmembrane proteins that play a critical role in cell growth and differentiation. KIDINS220 has been shown to be involved in a number of important cellular processes, including cell signaling, angiogenesis, and neuroprotection. As a result, KIDINS220 has potential as a drug target or biomarker for a variety of diseases.

The Importance of KIDINS220

KIDINS220 is a key regulator of several cellular processes that are critical for normal development and function. One of its most important functions is to regulate cell proliferation. KIDINS220 has been shown to play a role in the regulation of cell proliferation by allowing cells to access and utilize the extracellular signaling molecule, src. src is a transmembrane protein that is involved in a variety of cellular processes, including cell signaling and survival.

KIDINS220 has also been shown to be involved in the regulation of cell differentiation. During development, KIDINS220 helps to ensure that cells differentiate into the appropriate cell types. This is important for the development and maintenance of tissues and organs, and is critical for the development and treatment of many diseases.

In addition to its roles in cell proliferation and differentiation, KIDINS220 is also involved in the regulation of angiogenesis. Angiogenesis is the process by which new blood vessels are formed, and it is critical for the development of many tissues, including the brain and the kidneys . KIDINS220 has been shown to play a role in the regulation of angiogenesis by allowing vascular endothelial cells to produce vascular endothelial growth factor (VEGF).

Vascular endothelial growth factor (VEGF) is a transmembrane protein that is involved in the regulation of angiogenesis and the formation of new blood vessels. It is produced by the endothelial cells, which are the cells that line the blood vessels. VEGF plays a critical role in the regulation of angiogenesis by allowing vascular endothelial cells to produce and secrete large amounts of VEGF.

KIDINS220 has also been shown to be involved in the regulation of neuroprotection. Neuroprotection is the process by which the brain and other nervous system cells are protected from injury and disease. KIDINS220 has also been shown to play a role in the regulation of neuroprotection by allowing cell membranes on extracellular signaling molecules that produce neurotoxins, such as NO.

NO is an extracellular signaling molecule that plays an important role in the growth and development of the nervous system. It is released extracellularly by neurons and can affect communication between neurons and synapse formation. NO can also affect the release of cytokines and growth factors, thereby affecting the growth and development of the nervous system.

Targeting KIDINS220

KIDINS220 has the potential as a drug target or biomarker for a variety of diseases due to its involvement in multiple cellular processes. As a drug target, KIDINS220 may be targeted by small molecules or antibodies that can modulate its activity. be used to diagnose or monitor diseases associated with its regulation.

One approach to targeting KIDINS220 is to use small molecules that can modulate its activity. One such approach is the use of inhibitors of src signaling, which is a transmembrane protein that is involved in multiple cellular processes, including cell signaling and survival.

Another approach to targeting KIDINS220 is to use antibodies that can recognize and target its specific epitope. An epitope refers to a specific region on an antigen molecule. by using

Protein Name: Kinase D Interacting Substrate 220

Functions: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway

The "KIDINS220 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIDINS220 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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