Nucleoporin 188: A Promising Cancer Treatment and Biomarker (G23511)
Nucleoporin 188: A Promising Cancer Treatment and Biomarker
Nucleoporin 188 (NUP188) is a drug target and a biomarker that is being studied for its potential utility in cancer treatment. Nucleoporin 188 is a small molecule inhibitor of the nucleoporin gene, which encodes a protein called NUPORIN. This protein plays a critical role in cell division and is often expressed in high levels in cancer cells. By inhibiting the activity of NUPORIN, Nucleoporin 188 is thought to disrupt the ability of cancer cells to divide and grow.
One of the key advantages of Nucleoporin 188 is its ability to selectively target cancer cells, rather than healthy cells. This is because Nucleoporin 188 is designed to bind specifically to the NUPORIN protein, which is only expressed in high levels in cancer cells. By selectively targeting cancer cells, Nucleoporin 188 is able to reduce the risk of unintended side effects that may be associated with traditional cancer treatments.
Another potential advantage of Nucleoporin 188 is its ability to inhibit the growth of cancer cells in a dose-dependent manner. This means that the more Nucleoporin 188 is administered to cancer cells, the more effective it is at reducing their growth. This could make Nucleoporin 188 an effective treatment option for cancer patients who are experiencing rapid growth or who have not responded to traditional treatments.
In addition to its potential as a cancer treatment, Nucleoporin 188 is also being studied as a potential biomarker. This is because its ability to inhibit the growth of cancer cells can be used as a marker for the effectiveness of Nucleoporin 188. By measuring the growth of cancer cells before and after treatment with Nucleoporin 188, researchers can determine the drug's effectiveness and monitor its impact on cancer cells over time.
Overall, Nucleoporin 188 is a promising drug target and biomarker for cancer treatment. Its ability to selectively target cancer cells and inhibit their growth make it an attractive option for cancer treatments that are effective and safe. Further research is needed to determine the full potential of Nucleoporin 188 as a cancer treatment and to develop it as a reliable biomarker for cancer patients.
Protein Name: Nucleoporin 188
Functions: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope (Probable). Required for proper protein transport into the nucleus (PubMed:32275884)
The "NUP188 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUP188 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
NUP205 | NUP210 | NUP210L | NUP210P1 | NUP210P2 | NUP214 | NUP35 | NUP37 | NUP42 | NUP43 | NUP50 | NUP50-DT | NUP54 | NUP58 | NUP62 | NUP62CL | NUP85 | NUP88 | NUP93 | NUP98 | NUPR1 | NUPR2 | NUS1 | NUS1P1 | NUS1P3 | NUSAP1 | NUTF2 | NUTF2P4 | NUTM1 | NUTM2A | NUTM2A-AS1 | NUTM2B | NUTM2B-AS1 | NUTM2D | NUTM2E | NUTM2F | NUTM2G | NVL | NWD1 | NWD2 | NXF1 | NXF2 | NXF3 | NXF4 | NXF5 | NXN | NXNL1 | NXNL2 | NXPE1 | NXPE2 | NXPE3 | NXPE4 | NXPH1 | NXPH2 | NXPH3 | NXPH4 | NXT1 | NXT2 | NXTAR | NYAP1 | NYAP2 | NYNRIN | NYX | OACYLP | OAF | OARD1 | OAS1 | OAS2 | OAS3 | OASL | OAT | OATP1 | OAZ1 | OAZ2 | OAZ3 | OBI1 | OBI1-AS1 | OBP2A | OBP2B | OBSCN | OBSCN-AS1 | OBSL1 | OC90 | OCA2 | OCEL1 | OCIAD1 | OCIAD2 | OCLM | OCLN | OCLNP1 | OCM | OCM2 | OCRL | OCSTAMP | ODAD1 | ODAD2 | ODAD3 | ODAD4 | ODAM | ODAPH
