NUP42: A Potential Drug Target for Cancer (G11097)

Target Name: NUP42

NCBI ID: G11097

NUP42

NUP42: A Potential Drug Target for Cancer

Nucleoporin-like protein 1 (NUP42) is a protein that is expressed in various cell types of the human body, including epithelial, muscle, and neural cells. NUP42 is a nucleoporin, which is a protein that plays a crucial role in regulating the nuclear import of proteins into the cell.

One of the unique features of NUP42 is its ability to form a complex with small nucleopores, which are specialized pores in the nuclear membrane that allow the import of proteins. This complexation of NUP42 with small nucleopores allows the protein to physically interact with the nucleopores and regulate the import of proteins into the cell.

NUP42 has also been shown to play a role in the regulation of gene expression, specifically in the cell cycle. NUP42 has also been shown to interact with the protein kinase A-Tanapi, which is involved in the regulation of the cell cycle. This interaction between NUP42 and A-Tanapi have been shown to play a role in the regulation of cell proliferation and the establishment of cell cycle transitions.

In addition to its role in cell cycle regulation, NUP42 has also been shown to play a role in the regulation of cell survival. NUP42 has been shown to interact with the protein Bcl-2, which is a protein that plays a crucial role in the regulation of cell apoptosis, or cell death. This interaction between NUP42 and Bcl-2 has been shown to play a role in the regulation of cell survival and the resistance to chemotherapy.

NUP42 has also been shown to play a role in the regulation of cellular signaling pathways. NUP42 has been shown to interact with the protein Pyh, which is involved in the regulation of the PI3K/Akt signaling pathway. This interaction between NUP42 and Pyh has been shown to play a role in the regulation of cellular signaling pathways and the development of cancer.

Due to its unique combination of functions, NUP42 has been identified as a potential drug target and biomarker for a variety of diseases. For example, NUP42 has been shown to be overexpressed in various types of cancer, including breast, ovarian, and prostate cancer. This overexpression of NUP42 has been shown to play a role in the development and progression of these diseases.

In addition, NUP42 has also been shown to be involved in the regulation of cellular processes that are important for the development of cancer. For example, NUP42 has been shown to play a role in the regulation of cell adhesion, which is important for the development of cancer stem cells.

Overall, NUP42 is a protein that has a wide range of functions and has been shown to play a role in the regulation of various cellular processes that are important for the development and progression of cancer. As a result, NUP42 is a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of NUP42 in cellular processes and its potential as a drug.

Protein Name: Nucleoporin 42

Functions: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm

The "NUP42 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUP42 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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