TM4SF4: A promising drug target and biomarker for intestinal and liver tetraspan membrane protein

Target Name: TM4SF4

NCBI ID: G7104

TM4SF4

TM4SF4: A promising drug target and biomarker for intestinal and liver tetraspan membrane protein

TM4SF4 is a protein that is expressed in the intestinal and liver tissues. It is a member of the tetraspan family of proteins, which are known for their role in organizing various signaling pathways in cells. The most interesting feature of TM4SF4 is its potential as a drug target or biomarker. This article will discuss the molecular mechanisms of TM4SF4, its potential drug targets, and its potential as a biomarker for diseases such as cancer, obesity, and neurodegenerative disorders.

Molecular Mechanisms of TM4SF4

TM4SF4 is a 21-kDa protein that is expressed in the cytoplasm and endoplasmic reticulum of various cell types. It has a characteristic tetraspan structure, with four transmembrane domains and a cytoplasmic tail. TM4SF4 is involved in various signaling pathways, including cell signaling, DNA replication, and cell adhesion.

One of the unique features of TM4SF4 is its ability to form a tetraspan membrane in the cytoplasm. This structure is composed of four transmembrane domains that are connected by a cytoplasmic tail, and it is known as a tetraspan membrane protein (TMP). TM4SF4 functions as a negative regulator of the sphingomyelin syncergid lipids (SMAL1 and SMAL2), which are essential for the formation of the tetraspan membrane.

Potential Drug Targets

TM4SF4 has been identified as a potential drug target for various diseases, including cancer, obesity, and neurodegenerative disorders. One of the reasons for its potential as a drug target is its involvement in various signaling pathways. TM4SF4 is involved in the regulation of cell signaling, DNA replication, and cell adhesion, which are all critical for the development and progression of various diseases.

In cancer, TM4SF4 has been shown to play a negative role in the regulation of cell signaling, which is critical for the development of cancer cells. TM4SF4 has also been shown to be involved in the regulation of DNA replication, which is critical for the development of cancer cells. In addition, TM4SF4 has been shown to be involved in the regulation of cell adhesion, which is critical for the development of cancer cells.

In obesity, TM4SF4 has been shown to play a positive role in the regulation of cell signaling, which is critical for the development and progression of obesity. TM4SF4 has also been shown to be involved in the regulation of DNA replication, which is critical for the development and progression of obesity.

In neurodegenerative disorders, TM4SF4 has been shown to play a negative role in the regulation of cell signaling, which is critical for the development and progression of neurodegenerative disorders. TM4SF4 has also been shown to be involved in the regulation of DNA replication, which is critical for the development and progression of neurodegenerative disorders.

Potential Biomarkers

TM4SF4 has been shown to be involved in various signaling pathways, which makes it an attractive biomarker for diseases. One of the potential applications of TM4SF4 as a biomarker is its ability to be used as a therapeutic target for diseases. By inhibiting TM4SF4, researchers can target the regulation of cell signaling pathways and potentially treat diseases such as cancer, obesity, and neurodegenerative disorders.

In addition, TM4SF4 has been shown to be involved in

Protein Name: Transmembrane 4 L Six Family Member 4

Functions: Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation

The "TM4SF4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TM4SF4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets