Target Name: TM7SF2
NCBI ID: G7108
Review Report on TM7SF2 Target / Biomarker Content of Review Report on TM7SF2 Target / Biomarker
TM7SF2
Other Name(s): Delta(14)-sterol reductase TM7SF2 (isoform 1) | Delta(14)-sterol reductase | delta-14-SR | NET47 | Sterol delta14-reductase | sterol C14-reductase | Putative sterol reductase SR-1 | TM7SF2 variant 1 | Transmembrane 7 superfamily member 2 | DHCR14A | Transmembrane 7 superfamily member 2, transcript variant 1 | C14SR | 3-beta-hydroxysterol Delta (14)-reductase | C-14 sterol reductase | Sterol C14-reductase | Delta(14)-sterol reductase TM7SF2 | putative sterol reductase SR-1 | ANG1 | another new gene 1 protein | ERG24_HUMAN | transmembrane 7 superfamily member 2 | Delta-14-SR | Another new gene 1 protein

TM7SF2: A Potential Drug Target and Biomarker for Steroid Reductase Enzymes

Steroid hormones are essential for various physiological processes in the body, including growth and development, inflammation, and maintenance of cellular function. However, when the production of these hormones becomes imbalanced or disrupted, they can lead to various diseases, such as obesity, diabetes, and cancer. The primary targets of these diseases are the enzymes involved in the synthesis and degradation of steroids. One of these enzymes is TM7SF2 (Delta(14)-sterol reductase TM7SF2), an enzyme involved in the steroid 14-beta-hydroxysteroid dehydrogenase (14-beta-HSD) pathway. In this article, we will discuss TM7SF2 as a potential drug target and biomarker for steroid reduc

Protein Name: Transmembrane 7 Superfamily Member 2

Functions: Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis

The "TM7SF2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TM7SF2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TM7SF3 | TM9SF1 | TM9SF2 | TM9SF3 | TM9SF4 | TMA16 | TMA7 | TMBIM1 | TMBIM4 | TMBIM6 | TMC1 | TMC2 | TMC3 | TMC4 | TMC5 | TMC6 | TMC7 | TMC8 | TMCC1 | TMCC1-DT | TMCC2 | TMCC3 | TMCO1 | TMCO1-AS1 | TMCO2 | TMCO3 | TMCO4 | TMCO5A | TMCO5B | TMCO6 | TMED1 | TMED10 | TMED10P1 | TMED11P | TMED2 | TMED3 | TMED4 | TMED5 | TMED6 | TMED7 | TMED7-TICAM2 | TMED8 | TMED9 | TMEFF1 | TMEFF2 | TMEM100 | TMEM101 | TMEM102 | TMEM104 | TMEM105 | TMEM106A | TMEM106B | TMEM106C | TMEM107 | TMEM108 | TMEM109 | TMEM11 | TMEM114 | TMEM115 | TMEM116 | TMEM117 | TMEM119 | TMEM120A | TMEM120B | TMEM121 | TMEM121B | TMEM123 | TMEM125 | TMEM126A | TMEM126B | TMEM127 | TMEM128 | TMEM129 | TMEM130 | TMEM131 | TMEM131L | TMEM132A | TMEM132B | TMEM132C | TMEM132D | TMEM132D-AS1 | TMEM132E | TMEM132E-DT | TMEM133 | TMEM134 | TMEM135 | TMEM138 | TMEM139 | TMEM139-AS1 | TMEM140 | TMEM141 | TMEM143 | TMEM144 | TMEM145 | TMEM147 | TMEM147-AS1 | TMEM14A | TMEM14B | TMEM14C | TMEM14DP