OR13: Subfamily of Olfactory Receptors and GPCR (G138799)

OR13: Subfamily of Olfactory Receptors and GPCR

Olfactory receptor family 13 (OR13) is a subfamily of olfactory receptors, also known as ENaC (endocrine-retina-accessory) receptor. OR13 is a G protein-coupled receptor (GPCR), which means it is a transmembrane protein that spans the cell membrane and is involved in cell-cell and cell-extracellular signaling.

OR13 is expressed in the peripheral nervous system (PNS) and central nervous system (CNS), and is involved in the sense of smell. It is one of the five known subfamilies of OR13, which include OR13A, OR13B, OR13C, OR13D, and OR13E.

OR13 is a small molecule receptor that is activated by certain chemicals, such as odor molecules and small organic compounds. It is expressed in the sensory neurons that carry the sense of smell to the brain. OR13 is involved in the perception of a wide variety of scents, including sweet, sour, bitter, salty, and bitter.

OR13 is a GPCR, which means it is a transmembrane protein that spans the cell membrane and is involved in cell-cell and cell-extracellular signaling. GPCRs are a type of receptor that is involved in the sense of smell, as well as other functions such as pain perception and cardiovascular regulation.

OR13 is involved in the sense of smell by detecting the volatile molecules in the air. These molecules are the building blocks of many scents, and they are released by the glands and skin as a person inhales. The OR13 receptor is activated by the presence of these molecules, which triggers a signaling cascade that leads to the sensation of smell.

OR13 is a potential drug target in the sense of smell. Many diseases, including cancer, diabetes, and neurodegenerative disorders, are associated with changes in the sense of smell. Researchers are interested in developing drugs that can restore or enhance the sense of smell in people with these conditions. OR13 may be a useful biomarker for these diseases, as it is involved in the sense of smell and can be affected by changes in these conditions.

OR13 is also a potential biomarker for other diseases, such as smoking, alcohol use, and drug addiction. The sense of smell is often impaired in people who smoke or consume large amounts of alcohol, and may be influenced by other factors such as stress, anxiety, and depression. OR13 may be a useful indicator of these conditions and could be used as a target for drug treatment.

OR13 is also involved in the regulation of pain and inflammation. The sense of smell is involved in the regulation of pain and inflammation in the body, and may be influenced by changes in these conditions. OR13 may be a potential target for pain and inflammation treatments.

In conclusion, OR13 is a small molecule receptor that is involved in the sense of smell. It is a member of the Olfactory receptor family 13 and is expressed in the PNS and CNS. OR13 is involved in the perception of a wide variety of scents and may be a potential drug target for the sense of smell and other diseases. Further research is needed to fully understand the role of OR13 in the sense of smell and its potential as a drug target.

Protein Name: Olfactory Receptor Family 13 Subfamily C Member 5

Functions: Odorant receptor

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More Common Targets

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