GPSM2: A Protein Involved in Various Cellular Processes (G29899)

Target Name: GPSM2

NCBI ID: G29899

GPSM2

GPSM2: A Protein Involved in Various Cellular Processes

GPSM2, or G protein-coupled receptor 2 (GPCR2), is a protein that plays a crucial role in various cellular processes in the body. It is a member of the G protein-coupled receptor family, which is a large family of transmembrane proteins that play a significant role in cellular signaling. GPSM2 is a variant of the GPSM2 gene, which is located on chromosome 7 and encodes a protein with 184 amino acid residues.

GPSM2 is a protein that is expressed in many different tissues and organs, including the brain, heart, kidneys, and pancreas. It is primarily localized to the plasma membrane of various cell types, including epithelial cells, endothelial cells, and smooth muscle cells. GPSM2 is also known to be involved in several different signaling pathways, including the regulation of pain, inflammation, and blood pressure.

One of the key functions of GPSM2 is its role in pain signaling. GPSM2 is known to be involved in the regulation of pain perception and tolerance, as well as the regulation of pain modulation. It is thought to play a key role in the descending pain modulatory system, which is involved in the regulation of pain through the release of endogenous opioids.

GPSM2 is also involved in the regulation of inflammation and cellular responses to inflammation. It is known to be involved in the regulation of the chemokine network, which is involved in the recruitment of immune cells to sites of inflammation. It is also involved in the regulation of the production of pro-inflammatory cytokines, such as TNF-alpha and IL-1.

GPSM2 is also involved in the regulation of blood pressure. It is known to be involved in the regulation of blood pressure through the regulation of sodium channels in smooth muscle cells. This is thought to play a key role in the regulation of blood pressure and the maintenance of cardiovascular health.

In addition to its role in pain, inflammation, and blood pressure regulation, GPSM2 is also involved in several other cellular processes. It is known to be involved in the regulation of cell adhesion, cell migration, and the regulation of the cytoskeleton. It is also involved in the regulation of the production of neurotransmitters, such as dopamine and GABA.

Given its involvement in so many different cellular processes, GPSM2 is a promising drug target. There is a growing body of research that has identified potential small molecules that can modulate the activity of GPSM2, with the goal of developing new treatments for a variety of diseases. Some of the most promising candidates for modulating GPSM2 activity include natural compounds, such as those derived from plants and animals, as well as synthetic compounds, such as small molecules and pharmaceuticals.

In conclusion, GPSM2 is a protein that plays a crucial role in various cellular processes in the body. It is a member of the G protein-coupled receptor family and is involved in the regulation of pain, inflammation, and blood pressure. Given its involvement in so many different cellular processes, GPSM2 is a promising drug target with the potential to treat a variety of diseases. Further research is needed to fully understand the role of GPSM2 in cellular processes and to identify effective modulators of its activity.

Protein Name: G Protein Signaling Modulator 2

Functions: Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348). Required for cortical dynein-dynactin complex recruitment during metaphase (PubMed:22327364). Plays a role in metaphase spindle orientation (PubMed:22327364). Also plays an important role in asymmetric cell divisions (PubMed:21816348). Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity)

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•   general information;
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•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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