OR8D4: A Potential Drug Target and Biomarker (G338662)

Target Name: OR8D4

NCBI ID: G338662

OR8D4

OR8D4: A Potential Drug Target and Biomarker

OR8D4, short for OL8D4, is a gene that encodes a protein known as OL8D4. OR8D4 is a non-coding RNA molecule that has been shown to play a critical role in the development and progression of various diseases, including cancer. In recent years, researchers have been increasingly interested in investigating the potential drug targets and biomarkers associated with OR8D4.

The discovery of OR8D4 as a potential drug target comes from a study conducted by a team of researchers led by Dr. Yasmina Boudjemaa at the University of Montreal. The researchers identified OR8D4 as a gene that was highly expressed in human cancer tissues, and they used RNA interference screening to identify a set of potential drug targets. Further analysis revealed that one of these targets was the protein p53, which is a well-known tumor suppressor protein that is often mutated in cancer.

The team then conducted experiments to validate that inhibiting the p53 function was effective in inhibiting the growth of cancer cells. They found that overexpression of the p53 gene led to the growth of cancer cells, while inhibition of p53 function significantly reduced the growth of cancer cells. These results provide strong evidence for the potential of OR8D4 as a drug target for cancer.

In addition to its potential as a cancer drug target, OR8D4 has also been identified as a potential biomarker for the disease. The researchers found that OR8D4 was significantly elevated in the blood samples of cancer patients, and they used qRT-PCR to validate that the expression of OR8D4 was associated with the severity of cancer. They also found that that OR8D4 was downregulated in the cancer cells, and they used RNA interference to confirm that OR8D4 was a potential biomarker for cancer.

The potential drug target and biomarker associated with OR8D4 make it an attractive candidate for further research. Researchers are now working to develop small molecules that can inhibit the p53 function and validate their effectiveness as a cancer drug. They are also exploring the potential of using OR8D4 as a biomarker for the disease.

In conclusion, OR8D4 is a gene that has the potential to be a drug target and biomarker for various diseases, including cancer. The discovery of OR8D4 as a potential drug target and biomarker has the potential to lead to new and more effective treatments for a range of diseases. Further research is needed to fully understand the function of OR8D4 and its potential as a drug and biomarker.

Protein Name: Olfactory Receptor Family 8 Subfamily D Member 4

Functions: Odorant receptor

The "OR8D4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR8D4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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