Target Name: TMPRSS9
NCBI ID: G360200
Review Report on TMPRSS9 Target / Biomarker Content of Review Report on TMPRSS9 Target / Biomarker
TMPRSS9
Other Name(s): Transmembrane serine protease 9, transcript variant 1 | Serase-2 | Serase-3 | polyserase 1 | TMPRSS9 variant 1 | TMPS9_HUMAN | Transmembrane protease serine 9 | transmembrane protease serine 9 | Transmembrane protease serine 9 (isoform 1) | Polyserase-1 | polyserine protease 1 | transmembrane protease, serine 9 | Polyserine protease 1 | Polyserase-I | Serase-1 | polyserase-1 | polyserase-I | transmembrane serine protease 9

TMPRSS9: A Potential Drug Target and Biomarker

TMPRSS9, or Transmembrane serine protease 9, is a protein that is expressed in various cell types throughout the body. It is aserine proteases, which means it breaks down other proteins into their amino acid building blocks. This protein is of interest as a potential drug target and biomarker due to its unique structure and various functions in the body.

TMPRSS9 is a transmembrane protein, which means it spans the cell membrane and is involved in various signaling pathways. It is a key regulator of the TGF-β pathway, which is a well-known signaling pathway that regulates cell growth, differentiation, and survival. TMPRSS9 has been shown to play a crucial role in regulating the activity of the TGF-β pathway and has been linked to various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of TMPRSS9 is its role in the regulation of cell signaling pathways. It is a key regulator of the TGF-β pathway and has been shown to play a crucial role in the regulation of cell proliferation and differentiation. TMPRSS9 has been shown to promote the growth and survival of various cell types, including cancer cells. This suggests that it may be a useful drug target for the treatment of cancer.

In addition to its role in cell signaling pathways, TMPRSS9 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune responses and has been linked to various inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease. This suggests that it may be a useful biomarker for the diagnosis and treatment of inflammatory diseases.

TMPRSS9 has also been shown to play a role in the regulation of pain perception. It is involved in the regulation of the nociceptive pain pathway, which is the pathway that is responsible for the sensation of pain that is associated with injury or inflammation. This suggests that TMPRSS9 may be a useful drug target for the treatment of pain disorders.

In conclusion, TMPRSS9 is a protein that is expressed in various cell types throughout the body and is involved in various signaling pathways. It is a potential drug target and biomarker due to its unique structure and functions in the body. Further research is needed to fully understand the role of TMPRSS9 in the regulation of cell signaling pathways, inflammation, and pain perception.

Protein Name: Transmembrane Serine Protease 9

Functions: Serase-1 and serase-2 are serine proteases that hydrolyze the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC. In contrast, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Ala-Pro-Ala-AMC are not significantly hydrolyzed

The "TMPRSS9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMPRSS9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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