TMX2-CTNND1: A Drug Target / Disease Biomarker (G100528016)

Target Name: TMX2-CTNND1

NCBI ID: G100528016

TMX2-CTNND1

Other Name(s): TMX2-CTNND1 readthrough (NMD candidate) | p120(cas) | CTNND1 | CAS | p120(ctn)

TMX2-CTNND1: A Drug Target / Disease Biomarker

TMX2-CTNND1 is a protein that is expressed in the central nervous system (CNS) and has been shown to play a role in the development and progression of several neurological disorders, including Alzheimer's disease. The protein is a potential drug target (or biomarker) for the treatment of these disorders.

TMX2-CTNND1 is a member of the superfamily of transmembrane protein (SMP) family 2 (TMX2) and is a key regulator of the neural stem cell (NSC) lineage. It is expressed in the CNS and has been shown to localize to the endoplasmic reticulum (ER) and to play a role in the regulation of intracellular signaling pathways, including the TGF-β pathway.

The TGF-β pathway is a well-established pathway that plays a central role in the development and maintenance of neural stem cells and their differentiated progeny. TGF-β signaling is activated by several different factors, including mechanical stress, chemotactic factors, and neurotrophic factors. These factors induce the transcription of genes that promote stem cell proliferation and differentiation, as well as the regulation of cell survival and death.

TMX2-CTNND1 has been shown to play a role in the regulation of TGF-β signaling in the CNS. It has been shown to interact with several TGF-β signaling pathway components, including the transcription factor SMAD2 and the protein serine kinase PXXQ1. These interactions may play a role in the regulation of stem cell proliferation and differentiation in the CNS.

In addition to its role in TGF-β signaling, TMX2-CTNND1 has also been shown to play a role in the regulation of cellular processes that are important for the development and maintenance of neural stem cells, including the regulation of cell adhesion, migration, and survival.

TMX2-CTNND1 has been shown to play a role in the regulation of cell adhesion in the CNS. Adhesion is the process by which cells stick together to form tissues and organs. The regulation of cell adhesion is critical for the development and maintenance of neural stem cells and their differentiated progeny.

TMX2-CTNND1 has been shown to localize to the endoplasmic reticulum (ER) and to play a role in the regulation of ER-to-cytoskeleton fusion, which is a critical step in the regulation of cell adhesion. The ER-to-cytoskeleton fusion is the process by which new vesicles are formed in the ER and are targeted to the plasma membrane, where they become part of the cytoskeleton.

TMX2-CTNND1 has also been shown to play a role in the regulation of cellular migration in the CNS. Migration is the process by which cells move from one location to another in the body, and it is critical for the development and maintenance of neural stem cells and their differentiated progeny.

TMX2-CTNND1 has been shown to play a role in the regulation of cellular survival in the CNS. The regulation of cellular survival is critical for the development and maintenance of neural stem cells and their differentiated progeny. TMX2-CTNND1 has been shown to interact with several cellular stressors, including reactive oxygen species (ROS) and chemotactic factors, which can induce cellular stress and play a role in the regulation of cellular survival.

In conclusion, TMX2-CTNND1 is a protein that is expressed in the CNS and has been shown to play a role in the development and progression of several neurological disorders, including Alzheimer's disease. The protein is a potential drug target (or biomarker) for the treatment of these disorders. Its role in the regulation of TGF-β signaling, cell adhesion, migration, and survival may be

Protein Name: TMX2-CTNND1 Readthrough (NMD Candidate)

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•   general information;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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