TMEM212: A Potential Drug Target for Neurotransmission, Neuroendocrine Regulation and Renal Function

Target Name: TMEM212

NCBI ID: G389177

TMEM212

TMEM212: A Potential Drug Target for Neurotransmission, Neuroendocrine Regulation and Renal Function

TMEM212 (Tissue Membrane Model 212) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the superfamily of transmembrane protein (TM) transmembrane proteins (TMPs), which are involved in various physiological processes in the body, including signaling, ion transport, and modulation of cellular signaling pathways.

TMEM212 is a 21.1 kDa protein that is composed of 156 amino acid residues. It has a hydrophobic catalytic region at its extracellular domain, which is responsible for its membrane-spanning properties. The catalytic region of TMEM212 contains a catalytic cycle that is involved in the transfer of electrons from the substrate to the catalytic center, allowing it to catalyze various chemical reactions.

TMEM212 is also known as TM212_HUMAN, which is a human protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a potential drug target (or biomarker) due to its involvement in various physiological processes in the body, including neurotransmission, neuroendocrine regulation, and renal function.

One of the potential mechanisms by which TMEM212 may be involved in neurotransmission is through its role in the regulation of neurotransmitter release from axons. TMEM212 is known to be involved in the regulation of the release of neurotransmitters, such as dopamine, from axons in the central nervous system (CNS). This is done through its interaction with the protein postsynaptic density protein (PDZ), which is a protein that is involved in the regulation of neurotransmitter release from axons.

Another potential mechanism by which TMEM212 may be involved in neurotransmission is through its role in the regulation of neuroendocrine regulation. TMEM212 has been shown to be involved in the regulation of neuroendocrine regulated signaling pathways, such as the regulation of insulin secretion by pancreatic beta cells.

TMEM212 is also involved in renal function, which is done through its role in the regulation of water and electrolyte transport in the kidney. This is done through its interaction with the protein Aquaporin 1 (AQP1), which is involved in water and electrolyte transport in the body.

In conclusion, TMEM212 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the superfamily of transmembrane protein (TM) transmembrane proteins (TMPs), which are involved in various physiological processes in the body. TMEM212 is potential drug target (or biomarker) due to its involvement in neurotransmission, neuroendocrine regulation, and renal function. Further research is needed to fully understand the role of TMEM212 in the body and its potential as a drug target.

Protein Name: Transmembrane Protein 212

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•   general information;
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•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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